ARG64665
anti-SLC10A2 / ASBT antibody
anti-SLC10A2 / ASBT antibody for Western blot and Mouse
Cancer antibody; Metabolism antibody; Signaling Transduction antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes SLC10A2 / ASBT |
|---|---|
| Tested Reactivity | Ms |
| Tested Application | WB |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | SLC10A2 / ASBT |
| Antigen Species | Mouse |
| Immunogen | C-DETNKGFQPDEK |
| Conjugation | Un-conjugated |
| Alternate Names | Ileal sodium/bile acid cotransporter; ASBT; NTCP2; Apical sodium-dependent bile acid transporter; PBAM; Ileal sodium-dependent bile acid transporter; IBAT; Ileal Na; Solute carrier family 10 member 2; Na; Sodium/taurocholate cotransporting polypeptide, ileal; ISBT |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P70172 Mouse Ileal sodium/bile acid cotransporter |
|---|---|
| Gene Symbol | Slc10a2 |
| Gene Full Name | solute carrier family 10, member 2 |
| Background | This gene encodes a sodium/bile acid cotransporter. This transporter is the primary mechanism for uptake of intestinal bile acids by apical cells in the distal ileum. Bile acids are the catabolic product of cholesterol metabolism, so this protein is also critical for cholesterol homeostasis. Mutations in this gene cause primary bile acid malabsorption (PBAM); muatations in this gene may also be associated with other diseases of the liver and intestines, such as familial hypertriglyceridemia (FHTG). [provided by RefSeq, Mar 2010] |
| Function | Plays a critical role in the sodium-dependent reabsorption of bile acids from the lumen of the small intestine. Plays a key role in cholesterol metabolism (By similarity). [UniProt] |
| Research Area | Cancer antibody; Metabolism antibody; Signaling Transduction antibody |
| Calculated MW | 38 kDa |
Images (1) Click the Picture to Zoom In
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ARG64665 anti-SLC10A2 / ASBT antibody WB image
Western blot: Mouse Small Intestine lysate (35 µg protein in RIPA buffer) stained with ARG64665 anti-SLC10A2 / ASBT antibody at 0.5 µg/ml dilution.
