ARG44931
anti-SKIV2L antibody
anti-SKIV2L antibody for IHC-Formalin-fixed paraffin-embedded sections and Human
Overview
| Product Description | Mouse Monoclonal antibody recognizes SKIV2L |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Target Name | SKIV2L |
| Antigen Species | Human |
| Epitope | SEFPSRKDSK AHEQALAELT KRLGALEEPD MTGQLVDLPE YYSWGEELTE TQHMIQRRIM ESVNGLKSLS AGRVVVVKNQ EHHNALGVIL QVSSNSTSRV FTTLVLCDKP LSQDPQDRGP ATAEVPYPDD LVGFKLFLPE GPCDHTVVKL QPGDMAAITT KVLRVNGEKI LEDFSKRQQP KFKKDPPLAA VTTAVQELLR LAQAHPAGPP TLDPVNDLQL KDMSVVEGGL RARKLEELIQ GAQCVHSPRF PAQYLKLRER MQIQKEMERL |
| Conjugation | Un-conjugated |
| Alternate Names | SKIC2; SKI2 Subunit Of Superkiller Complex; DDX13; SKI2W; HLP; SKIV2L1; SKIV2L; SKIV2; 170A; SKI2; SKI2 Homolog, Superkiller Viralicidic Activity 2-Like; Superkiller Complex Protein 2; Ski2 Like RNA Helicase; Helicase-Like Protein; Superkiller Viralicidic Activity 2 (S. Cerevisiae Homolog)-Like; Superkiller Viralicidic Activity 2-Like (S. Cerevisiae); SKI2 Subunit Of Superkiller Complex Protein; Superkiller Viralicidic Activity 2-Like; Helicase SKI2W; EC 3.6.4.13; EC 3.6.1; THES2; Ski2; W |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Protein A purification |
| Buffer | PBS with 0.09% sodium azide |
| Preservative | 0.09% sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | SKIV2L |
| Gene Full Name | SKI2 Subunit Of Superkiller Complex |
| Background | DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a human homologue of yeast SKI2 and may be involved in antiviral activity by blocking translation of poly(A) deficient mRNAs. This gene is located in the class III region of the major histocompatibility complex. [provided by RefSeq, Jul 2008] |
| Function | In the nucleus, the SKI complex associates with transcriptionally active genes in a manner dependent on PAF1 complex (PAF1C) |
| Cellular Localization | Cytoplasm, Nucleus |
| Calculated MW | 138 kDa |
| PTM | Phosphoprotein |
Images (1) Click the Picture to Zoom In
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ARG44931 anti-SKIV2L antibody IHC-P image
Immunohistochemistry: Human stomach stained with ARG44931 anti-SKIV2L antibody at 5 µg/mL dilution.
