ARG45272
anti-SHQ1 antibody
anti-SHQ1 antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Polyclonal antibody recognizes SHQ1 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | SHQ1 |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human SHQ1. |
| Conjugation | Un-conjugated |
| Alternate Names | SHQ1, H/ACA Ribonucleoprotein Assembly Factor; Shq1p; Protein SHQ1 Homolog; FLJ10539; Gene Associated With Retinoid And Interferon-Induced Mortality 1; SHQ1 Homolog (S. Cerevisiae); SHQ1 Homolog; GRIM-1; DYT35; NEDDS |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| Observed Size | 80 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | SHQ1 |
| Gene Full Name | SHQ1, H/ACA Ribonucleoprotein Assembly Factor |
| Background | SHQ1 assists in the assembly of H/ACA-box ribonucleoproteins that function in the processing of ribosomal RNAs, modification of spliceosomal small nuclear RNAs, and stabilization of telomerase (see MIM 602322) (Grozdanov et al., 2009 [PubMed 19383767]).[supplied by OMIM, Dec 2010] |
| Function | Required for the quantitative accumulation of H/ACA ribonucleoproteins (RNPs), including telomerase, probably through the stabilization of DKC1, from the time of its synthesis until its association with NOP10, NHP2, and NAF1 at the nascent H/ACA RNA. [UniProt] |
| Cellular Localization | Cytoplasm; Nucleus. [UniProt] |
| Calculated MW | 65 kDa |
Images (6) Click the Picture to Zoom In
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ARG45272 anti-SHQ1 antibody IHC-P image
Immunohistochemistry: Human renal cancer stained with ARG45272 anti-SHQ1 antibody at 2 μg/ml dilution.
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ARG45272 anti-SHQ1 antibody ICC/IF image
Immunofluorescence: A549 stained with ARG45272 anti-SHQ1 antibody at 5 ug/ml dilution.
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ARG45272 anti-SHQ1 antibody WB image
Western blot: A549 and 293T stained with ARG45272 anti-SHQ1 antibody at 0.5 μg/ml dilution.
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ARG45272 anti-SHQ1 antibody FACS image
Flow Cytometry: A549 stained with ARG45272 anti-SHQ1 antibody at 1 µg/10^6 cells dilution.
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ARG45272 anti-SHQ1 antibody IHC-P image
Immunohistochemistry: Rat kidney stained with ARG45272 anti-SHQ1 antibody at 2 μg/ml dilution.
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ARG45272 anti-SHQ1 antibody IHC-P image
Immunohistochemistry: Mouse kidney stained with ARG45272 anti-SHQ1 antibody at 2 μg/ml dilution.
