ARG40519

anti-SGLT2 antibody

anti-SGLT2 antibody for Western blot and Mouse

Overview

Product Description Rabbit Polyclonal antibody recognizes SGLT2
Tested Reactivity Ms
Predict Reactivity Hu, Rat, Cow, Dog, Gpig, Hrs, Rb
Tested Application WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name SGLT2
Antigen Species Mouse
Immunogen Synthetic peptide from Mouse SGLT2. (within the following region: SSTCYQPRPDSYHLLRDPVTGDLPWPALLLGLTIVSGWYWCSDQVIVQRC)
Conjugation Un-conjugated
Alternate Names Na; Solute carrier family 5 member 2; Sodium/glucose cotransporter 2; SGLT2; Low affinity sodium-glucose cotransporter

Application Instructions

Predict Reactivity Note Predicted Homology Based On Immunogen Sequence: Cow: 93%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Rabbit: 93%; Rat: 93%
Application Suggestion
Tested Application Dilution
WB1 ug/ml
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Affinity purified.
Buffer PBS, 0.09% (w/v) Sodium azide and 2% Sucrose.
Preservative 0.09% (w/v) Sodium azide
Stabilizer 2% Sucrose
Concentration Batch dependent: 0.5 - 1 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 246787 Mouse SLC5A2

Swiss-port # Q923I7 Mouse Sodium/glucose cotransporter 2

Gene Symbol SLC5A2
Gene Full Name solute carrier family 5 (sodium/glucose cotransporter), member 2
Background This gene encodes a member of the sodium glucose cotransporter family which are sodium-dependent glucose transport proteins. The encoded protein is the major cotransporter involved in glucose reabsorption in the kidney. Mutations in this gene are associated with renal glucosuria. Two transcript variants, one protein-coding and one not, have been found for this gene. [provided by RefSeq, Feb 2015]
Function Sodium-dependent glucose transporter. Has a Na(+) to glucose coupling ratio of 1:1.

Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na(+)/glucose cotransporter arranged in series along kidney proximal tubules. [UniProt]
Cellular Localization Membrane; Multi-pass membrane protein. [UniProt]
Calculated MW 73 kDa

Images (1) Click the Picture to Zoom In

  • ARG40519 anti-SGLT2 antibody WB image

    Western blot: Mouse thymus lysate stained with ARG40519 anti-SGLT2 antibody at 1 ug/ml dilution.