ARG41710

anti-SGCG / gamma Sarcoglycan antibody

anti-SGCG / gamma Sarcoglycan antibody for IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human

Overview

Product Description Rabbit Polyclonal antibody recognizes SGCG / gamma Sarcoglycan
Tested Reactivity Hu
Tested Application IHC-P, IP, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name SGCG / gamma Sarcoglycan
Antigen Species Human
Immunogen Synthetic peptide of Human SGCG / gamma Sarcoglycan
Conjugation Un-conjugated
Alternate Names 35DAG; DMDA1; TYPE; SCG3; DMDA; Gamma-sarcoglycan; DAGA4; 35 kDa dystrophin-associated glycoprotein; A4; SCARMD2; Gamma-SG; LGMD2C; MAM

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P1:50 - 1:200
IP1:50
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Observed Size ~ 32 kDa

Properties

Form Liquid
Purification Affinity purified.
Buffer PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 6445 Human SGCG

Swiss-port # Q13326 Human Gamma-sarcoglycan

Gene Symbol SGCG
Gene Full Name sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
Background This gene encodes gamma-sarcoglycan, one of several sarcolemmal transmembrane glycoproteins that interact with dystrophin. The dystrophin-glycoprotein complex (DGC) spans the sarcolemma and is comprised of dystrophin, syntrophin, alpha- and beta-dystroglycans and sarcoglycans. The DGC provides a structural link between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. Defects in the encoded protein can lead to early onset autosomal recessive muscular dystrophy, in particular limb-girdle muscular dystrophy, type 2C (LGMD2C). [provided by RefSeq, Oct 2008]
Function Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix. [UniProt]
Cellular Localization Cell membrane, sarcolemma; Single-pass type II membrane protein. Cytoplasm, cytoskeleton. [UniProt]
Calculated MW 32 kDa

Images (1) Click the Picture to Zoom In

  • ARG41710 anti-SGCG / gamma Sarcoglycan antibody WB image

    Western blot: Human skeletal muscle lysate stained with ARG41710 anti-SGCG / gamma Sarcoglycan antibody.