ARG59090
anti-SGCA / alpha Sarcoglycan antibody
anti-SGCA / alpha Sarcoglycan antibody for ICC/IF,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes SGCA / alpha Sarcoglycan |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | SGCA / alpha Sarcoglycan |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 60-290 of Human SGCA / alpha Sarcoglycan (NP_000014.1). |
| Conjugation | Un-conjugated |
| Alternate Names | adhalin; Adhalin; 50 kDa dystrophin-associated glycoprotein; Alpha-sarcoglycan; 50-DAG; Alpha-SG; SCARMD1; DMDA2; 50DAG; Dystroglycan-2; A2; DAG2; ADL; LGMD2D |
Application Instructions
| Application Suggestion |
|
||||||
|---|---|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Positive Control | A549 | ||||||
| Observed Size | 43kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | SGCA |
| Gene Full Name | sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein) |
| Background | This gene encodes a component of the dystrophin-glycoprotein complex (DGC), which is critical to the stability of muscle fiber membranes and to the linking of the actin cytoskeleton to the extracellular matrix. Its expression is thought to be restricted to striated muscle. Mutations in this gene result in type 2D autosomal recessive limb-girdle muscular dystrophy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008] |
| Function | Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix. [UniProt] |
| Cellular Localization | Cell membrane, sarcolemma; Single-pass type I membrane protein. Cytoplasm, cytoskeleton. [UniProt] |
| Calculated MW | 43 kDa |
Images (1) Click the Picture to Zoom In
-
ARG59090 anti-SGCA / alpha Sarcoglycan antibody WB image
Western blot: 25 µg of A549 cell lysate stained with ARG59090 anti-SGCA / alpha Sarcoglycan antibody at 1:3000 dilution.
