ARG45622
anti-SEC23IP antibody
anti-SEC23IP antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat,Monkey
Overview
| Product Description | Rabbit Polyclonal antibody recognizes SEC23IP |
|---|---|
| Tested Reactivity | Hu, Ms, Rat, Mk |
| Tested Application | FACS, ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | SEC23IP |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human SEC23IP. |
| Conjugation | Un-conjugated |
| Alternate Names | SEC23IP; SEC23 Interacting Protein; P125; IPLA1beta; P125A; Intracellular Phospholipase A1 Beta; SEC23-Interacting Protein; MSTP053; IPLA1β; IPLA1A; IPLA1B |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| Observed Size | 125 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | SEC23IP |
| Gene Full Name | SEC23 Interacting Protein |
| Background | This gene encodes a member of the phosphatidic acid preferring-phospholipase A1 family. The encoded protein is localized to endoplasmic reticulum exit sites and plays a critical role in ER-Golgi transport as part of the multimeric coat protein II complex. An orthologous gene in frogs is required for normal neural crest cell development, suggesting that this gene may play a role in Waardenburg syndrome neural crest defects. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Feb 2011] |
| Function | Plays a role in the organization of endoplasmic reticulum exit sites. Specifically binds to phosphatidylinositol 3-phosphate (PI(3)P), phosphatidylinositol 4-phosphate (PI(4)P) and phosphatidylinositol 5-phosphate (PI(5)P). [UniProt] |
| Cellular Localization | Cytoplasmic vesicle; Endoplasmic reticulum; Membrane. [UniProt] |
| Calculated MW | 111 kDa |
| PTM | Phosphoprotein. [UniProt] |
Images (9) Click the Picture to Zoom In
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ARG45622 anti-SEC23IP antibody IHC-P image
Immunohistochemistry: Human colon adenocarcinoma stained with ARG45622 anti-SEC23IP antibody at 2 μg/ml dilution.
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ARG45622 anti-SEC23IP antibody ICC/IF image
Immunofluorescence: A549 stained with ARG45622 anti-SEC23IP antibody at 5 μg/ml dilution.
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ARG45622 anti-SEC23IP antibody WB image
Western blot: Hela and 293T stained with ARG45622 anti-SEC23IP antibody at 0.5 μg/ml dilution.
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ARG45622 anti-SEC23IP antibody FACS image
Flow Cytometry: HL-60 stained with ARG45622 anti-SEC23IP antibody at 1 µg/10^6 cells dilution.
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ARG45622 anti-SEC23IP antibody IHC-P image
Immunohistochemistry: Rat testis stained with ARG45622 anti-SEC23IP antibody at 2 μg/ml dilution.
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ARG45622 anti-SEC23IP antibody WB image
Western blot: Rat brain stained with ARG45622 anti-SEC23IP antibody at 0.5 μg/ml dilution.
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ARG45622 anti-SEC23IP antibody IHC-P image
Immunohistochemistry: Mouse testis stained with ARG45622 anti-SEC23IP antibody at 2 μg/ml dilution.
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ARG45622 anti-SEC23IP antibody WB image
Western blot: RAW264.7 stained with ARG45622 anti-SEC23IP antibody at 0.5 μg/ml dilution.
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ARG45622 anti-SEC23IP antibody WB image
Western blot: COS-7 stained with ARG45622 anti-SEC23IP antibody at 0.5 μg/ml dilution.
