ARG44023
anti-SDHD antibody
anti-SDHD antibody for ICC/IF,Western blot and Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes SDHD |
|---|---|
| Tested Reactivity | Ms |
| Predict Reactivity | Hu, Rat, Bov, Sheep |
| Tested Application | ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | SDHD |
| Antigen Species | Human |
| Immunogen | Human SDHD recombinantprotein |
| Conjugation | Un-conjugated |
| Protein Full Name | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial |
| Alternate Names | SDHD; Succinate Dehydrogenase Complex Subunit D; CybS; Succinate Dehydrogenase [Ubiquinone] Cytochrome B Small Subunit, Mitochondrial; Succinate-Ubiquinone Oxidoreductase Cytochrome B Small Subunit; Succinate-Ubiquinone Reductase Membrane Anchor Subunit; CII-4; PGL1; QPs3; SDH4; PGL; Succinate Dehydrogenase Complex, Subunit D, Integral Membrane Protein; Succinate Dehydrogenase Complex Subunit D Integral Membrane Protein; Small Subunit Of Cytochrome B; MC2DN3; CBT1; CWS3 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Buffer | PBS containing 0.02% sodium azide |
| Preservative | 0.02% sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Bioinformation
| Database Links |
Swiss-port # Q9CXV1 Mouse Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochond |
|---|---|
| Gene Symbol | SDHD |
| Gene Full Name | Succinate Dehydrogenase Complex Subunit D |
| Background | This gene encodes a member of complex II of the respiratory chain, which is responsible for the oxidation of succinate. The encoded protein is one of two integral membrane proteins anchoring the complex to the matrix side of the mitochondrial inner membrane. Mutations in this gene are associated with the formation of tumors, including hereditary paraganglioma. Transmission of disease occurs almost exclusively through the paternal allele, suggesting that this locus may be maternally imprinted. There are pseudogenes for this gene on chromosomes 1, 2, 3, 7, and 18. Alternative splicing results in multiple transcript variants. |
| Function | Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone. |
| Cellular Localization | Membrane, Mitochondrion, Mitochondrion inner membrane |
| Calculated MW | 17 kDa |
Images (2) Click the Picture to Zoom In
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ARG44023 anti-SDHD antibody ICC/IF image
Immunofluorescence: EL4 stained with ARG44023 anti-SDHD antibody at 20 μg/mL dilution.
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ARG44023 anti-SDHD antibody WB image
Western blot: EL4 stained with ARG44023 anti-SDHD antibody at 2 μg/mL dilution.
