ARG43633
anti-SCP3 antibody
anti-SCP3 antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes SCP3 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | SCP3 |
| Antigen Species | Human |
| Immunogen | Recombinant protein fragment corresponding to a.a. 75-236 of Human SCP3 protein. |
| Conjugation | Un-conjugated |
| Protein Full Name | Synaptonemal complex protein 3 |
| Alternate Names | Synaptonemal complex protein 3; SPGF4; COR1; SCP-3; SCP3 |
Application Instructions
| Application Suggestion |
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| Application Note | IHC-P: Antigen Retrieval: Boil tissue section in EDTA buffer (pH 8.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
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| Observed Size | ~ 30-35 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | SYCP3 |
| Gene Full Name | synaptonemal complex protein 3 |
| Background | This gene encodes an essential structural component of the synaptonemal complex. This complex is involved in synapsis, recombination and segregation of meiotic chromosomes. Mutations in this gene are associated with azoospermia in males and susceptibility to pregnancy loss in females. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, May 2010] |
| Function | Component of the transverse filaments of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Has an essential meiotic function in spermatogenesis. May be important for testis development. Required for efficient phosphorylation of HORMAD1 and HORMAD2 (By similarity). [UniProt] |
| Cellular Localization | Centromere; Chromosome; Nucleus |
| Calculated MW | 28 kDa |
| PTM | Phosphorylated. [UniProt] |
Images (6) Click the Picture to Zoom In
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ARG43633 anti-SCP3 antibody IHC-P image
Immunohistochemistry: Human gall bladder adenosquamous carcinoma stained with ARG43633 anti-SCP3 antibody at 2 μg/ml dilution.
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ARG43633 anti-SCP3 antibody ICC/IF image
Immunofluorescence: A549 stained with ARG43633 anti-SCP3 antibody at 5 μg/ml dilution.
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ARG43633 anti-SCP3 antibody WB image
Western blot: HepG2 stained with ARG43633 anti-SCP3 antibody at 0.5 μg/mL dilution.
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ARG43633 anti-SCP3 antibody FACS image
Flow Cytometry: JK stained with ARG43633 anti-SCP3 antibody at 1 μg / 10^6 cells dilution.
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ARG43633 anti-SCP3 antibody WB image
Western blot: Rat testis and C6 stained with ARG43633 anti-SCP3 antibody at 0.5 μg/mL dilution.
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ARG43633 anti-SCP3 antibody WB image
Western blot: Mouse testis stained with ARG43633 anti-SCP3 antibody at 0.5 μg/mL dilution.
