ARG57885

anti-S100A6 antibody

anti-S100A6 antibody for ICC/IF,Western blot and Human,Mouse,Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes S100A6
Tested Reactivity Hu, Ms, Rat
Tested Application ICC/IF, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name S100A6
Antigen Species Human
Immunogen Recombinant fusion protein corresponding to aa. 1-90 of Human S100A6 (NP_055439.1).
Conjugation Un-conjugated
Alternate Names S100 calcium-binding protein A6; PRA; MLN 4; 5B10; Prolactin receptor-associated protein; CACY; Growth factor-inducible protein 2A9; Protein S100-A6; Calcyclin; CABP; 2A9

Application Instructions

Application Suggestion
Tested Application Dilution
ICC/IF1:50 - 1:200
WB1:200 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control HT-29
Observed Size 10 kDa

Properties

Form Liquid
Purification Affinity purified.
Buffer PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 20200 Mouse S100A6

GeneID: 6277 Human S100A6

GeneID: 85247 Rat S100A6

Gene Symbol S100A6
Gene Full Name S100 calcium binding protein A6
Background The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma. [provided by RefSeq, Jul 2008]
Function May function as calcium sensor and modulator, contributing to cellular calcium signaling. May function by interacting with other proteins, such as TPR-containing proteins, and indirectly play a role in many physiological processes such as the reorganization of the actin cytoskeleton and in cell motility. Binds 2 calcium ions. Calcium binding is cooperative. [UniProt]
Cellular Localization Nucleus envelope, Cytoplasm, Cell membrane, Peripheral membrane protein, Cytoplasmic side. [UniProt]
Calculated MW 10 kDa
PTM The N-terminus is blocked. [UniProt]

Images (1) Click the Picture to Zoom In

  • ARG57885 anti-S100A6 antibody WB image

    Western blot: 25 µg of HT-29 cell lysate stained with ARG57885 anti-S100A6 antibody at 1:1000 dilution.