ARG57565
anti-RPGRIP1 antibody
anti-RPGRIP1 antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes RPGRIP1 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | FACS, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | RPGRIP1 |
| Antigen Species | Human |
| Immunogen | KLH-conjugated synthetic peptide corresponding to aa. 530-557 (Center) of Human RPGRIP1. |
| Conjugation | Un-conjugated |
| Alternate Names | CORD13; X-linked retinitis pigmentosa GTPase regulator-interacting protein 1; RPGR-interacting protein 1; RGRIP; LCA6; RPGRIP1d; RGI1; RPGRIP |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Positive Control | HL-60 |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A and immunogen peptide. |
| Buffer | PBS and 0.09% (W/V) Sodium azide. |
| Preservative | 0.09% (W/V) Sodium azide. |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q96KN7 Human X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 |
|---|---|
| Gene Symbol | RPGRIP1 |
| Gene Full Name | retinitis pigmentosa GTPase regulator interacting protein 1 |
| Background | This gene encodes a photoreceptor protein that interacts with retinitis pigmentosa GTPase regulator protein and is a key component of cone and rod photoreceptor cells. Mutations in this gene lead to autosomal recessive congenital blindness. [provided by RefSeq, Oct 2008] |
| Function | May function as scaffolding protein. Required for normal location of RPGR at the connecting cilium of photoreceptor cells. Required for normal disk morphogenesis and disk organization in the outer segment of photoreceptor cells and for survival of photoreceptor cells. [UniProt] |
| Cellular Localization | Cell projection, cilium. Note=Situated between the axonemal microtubules and the plasma membrane {ECO:0000250|UniProtKB:Q9EPQ2} |
| Calculated MW | 147 kDa |
Images (3) Click the Picture to Zoom In
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ARG57565 anti-RPGRIP1 antibody IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded Human breast carcinoma tissue stained with ARG57565 anti-RPGRIP1 antibody.
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ARG57565 anti-RPGRIP1 antibody WB image
Western blot: 35 µg of HL-60 cell lysate stained with ARG57565 anti-RPGRIP1 antibody.
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ARG57565 anti-RPGRIP1 antibody FACS image
Flow Cytometry: MDA-MB-231 cells stained with ARG57565 anti-RPGRIP1 antibody (bottom histogram) or without primary antibody as control (top histogram), followed by incubation with FITC labelled secondary antibody.
