ARG41814
anti-RIOX2 / MINA53 antibody
anti-RIOX2 / MINA53 antibody for ICC/IF,Western blot and Human,Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes RIOX2 / MINA53 |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | RIOX2 / MINA53 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide of Human RIOX2 / MINA53. |
| Conjugation | Un-conjugated |
| Alternate Names | MDIG; Mineral dust-induced gene protein; Histone lysine demethylase MINA; Nucleolar protein 52; ROX; Bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA; MINA53; 60S ribosomal protein L27a histidine hydroxylase; NO52; EC 1.14.11.-; Ribosomal oxygenase MINA; MYC-induced nuclear antigen |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Positive Control | A431 | ||||||
| Observed Size | ~ 50 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q8CD15 Mouse Bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA Swiss-port # Q8IUF8 Human Bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA |
|---|---|
| Gene Symbol | MINA |
| Gene Full Name | MYC induced nuclear antigen |
| Background | MINA is a c-Myc (MYC; MIM 190080) target gene that may play a role in cell proliferation or regulation of cell growth. (Tsuneoka et al., 2002 [PubMed 12091391]; Zhang et al., 2005 [PubMed 15897898]).[supplied by OMIM, May 2008] |
| Function | Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Is involved in the demethylation of trimethylated 'Lys-9' on histone H3 (H3K9me3), leading to an increase in ribosomal RNA expression. Also catalyzes the hydroxylation of 60S ribosomal protein L27a on 'His-39'. May play an important role in cell growth and survival. May be involved in ribosome biogenesis, most likely during the assembly process of pre-ribosomal particles. [UniProt] |
| Cellular Localization | Nucleus. Nucleus, nucleolus. [UniProt] |
| Calculated MW | 53 kDa |
Images (1) Click the Picture to Zoom In
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ARG41814 anti-RIOX2 / MINA53 antibody WB image
Western blot: A431 cell lysate stained with ARG41814 anti-RIOX2 / MINA53 antibody.
