ARG64092

anti-RASAL antibody

anti-RASAL antibody for Western blot and Human

Cancer antibody; Signaling Transduction antibody

Overview

Product Description Goat Polyclonal antibody recognizes RASAL
Tested Reactivity Hu
Tested Application WB
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name RASAL
Antigen Species Human
Immunogen C-QERGKAALGPLGP
Conjugation Un-conjugated
Alternate Names RASAL; RasGAP-activating-like protein 1

Application Instructions

Application Suggestion
Tested Application Dilution
WB0.3 - 1 µg/ml
Application Note WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 8437 Human RASAL1

Swiss-port # O95294 Human RasGAP-activating-like protein 1

Background The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. These proteins stimulate the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member contains domains which are characteristic of the GAP1 subfamily of RasGAP proteins but, in contrast to the other GAP1 family members, this protein is strongly and selectively expressed in endocrine tissues. Alternatively spliced transcript variants that encode different isoforms have been described [provided by RefSeq, Jul 2010]
Research Area Cancer antibody; Signaling Transduction antibody
Calculated MW 90 kDa

Images (1) Click the Picture to Zoom In

  • ARG64092 anti-RASAL antibody WB image

    Western Blot: Human Thyroid lysate (35 µg protein in RIPA buffer) stained with ARG64092 anti-RASAL antibody at 0.3 µg/ml dilution.