ARG63366
anti-RANBP8 / IPO8 antibody
anti-RANBP8 / IPO8 antibody for IHC-Formalin-fixed paraffin-embedded sections and Human
Gene Regulation antibody; Signaling Transduction antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes RANBP8 / IPO8 |
|---|---|
| Tested Reactivity | Hu |
| Predict Reactivity | Cow, Dog, Pig |
| Tested Application | IHC-P |
| Specificity | This antibody is expected to recognise isoform 1 (NP_006381.2) and isoform 2 (NP_001177924.1). |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | RANBP8 / IPO8 |
| Antigen Species | Human |
| Immunogen | C-SAFNFGTVPSNN |
| Conjugation | Un-conjugated |
| Alternate Names | Imp8; Importin-8; Ran-binding protein 8; RANBP8; RanBP8 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | IHC-P: Antigen Retrieval: Steam tissue section in Tris/EDTA buffer (pH 9.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Background | The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. This protein binds to the nuclear pore complex and, along with RanGTP and RANBP1, inhibits the GAP stimulation of the Ran GTPase. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010] |
| Research Area | Gene Regulation antibody; Signaling Transduction antibody |
| Calculated MW | 120 kDa |
Images (1) Click the Picture to Zoom In
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ARG63366 anti-RANBP8 / IPO8 antibody IHC-P image
Immunohistochemistry: paraffin embedded Human Tonsil. (Steamed antigen retrieval with Tris/EDTA buffer pH 9) stained with ARG63366 anti-RANBP8 / IPO8 antibody at 4 µg/ml dilution followed by HRP-staining. Similar results were obtained after antigen retrieval at pH9.
