ARG43922
anti-RAGE antibody
anti-RAGE antibody for Western blot and Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes RAGE |
|---|---|
| Tested Reactivity | Ms, Rat |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Target Name | RAGE |
| Antigen Species | Mouse |
| Immunogen | Mouse RAGE recombinant protein |
| Expression System | E.coli |
| Conjugation | Un-conjugated |
| Protein Full Name | Advanced glycosylation end product-specific receptor |
| Alternate Names | AGER; Advanced Glycosylation End-Product Specific Receptor; RAGE; SCARJ1; SRAGE; Advanced Glycosylation End Product-Specific Receptor; Receptor For Advanced Glycation End-Products; Receptor For Advanced Glycosylation End Products |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Buffer | 0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Bioinformation
| Gene Symbol | AGER |
|---|---|
| Gene Full Name | Advanced Glycosylation End-Product Specific Receptor |
| Background | The advanced glycosylation end product (AGE) receptor encoded by this gene is a member of the immunoglobulin superfamily of cell surface receptors. It is a multiligand receptor, and besides AGE, interacts with other molecules implicated in homeostasis, development, and inflammation, and certain diseases, such as diabetes and Alzheimer's disease. Many alternatively spliced transcript variants encoding different isoforms, as well as non-protein-coding variants, have been described for this gene. |
| Function | Cell surface pattern recognition receptor that senses endogenous stress signals with a broad ligand repertoire including advanced glycation end products, S100 proteins, high-mobility group box 1 protein/HMGB1, amyloid beta/APP oligomers, nucleic acids, phospholipids and glycosaminoglycans. |
| Cellular Localization | Cell membrane, Membrane, Secreted |
| Calculated MW | 43 kDa |
| PTM | Disulfide bond, Glycoprotein, Phosphoprotein, Ubl conjugation |
Images (1) Click the Picture to Zoom In
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ARG43922 anti-RAGE antibody WB image
Western blot: Rat lung and Mouse lung stained with ARG43922 anti-RAGE antibody at 0.5 μg/mL dilution.
