ARG43876
anti-RAB39A/B antibody
anti-RAB39A/B antibody for ELISA,Flow cytometry,ICC/IF,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes RAB39A and RAB39B |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA, FACS, ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Target Name | RAB39A / RAB39B |
| Antigen Species | Human |
| Immunogen | Human RAB39A/B recombinant protein |
| Expression System | E.coli |
| Conjugation | Un-conjugated |
| Protein Full Name | Ras-related protein Rab-39A / Ras-related protein Rab-39B |
| Alternate Names | RAB39A; RAB39A, Member RAS Oncogene Family; RAB39; RAB39, Member RAS Oncogene Family; Rab-Related GTP-Binding Protein; Ras-Related Protein Rab-39A; Rab-39; K28;RAB39B; RAB39B, Member RAS Oncogene Family; Ras-Related Protein Rab-39B; Waisman Syndrome; MRX72; WSN; Mental Retardation, X-Linked 72; XLID72; BGMR; WSMN |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Buffer | 0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Bioinformation
| Gene Symbol | RAB39A / RAB39B |
|---|---|
| Gene Full Name | RAB39A, Member RAS Oncogene Family / RAB39B, Member RAS Oncogene Family |
| Background | Predicted to enable GTPase activity. Involved in phagosome acidification and phagosome-lysosome fusion. Located in phagocytic vesicle. [provided by Alliance of Genome Resources, Apr 2022] |
| Function | Plays a role in the maturation and acidification of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Plays a role in vesicular trafficking. Plays a role in the fusion of phagosomes with lysosomes. Negatively regulates LPS-induced autophagosome formation in macrophages possibly by implicating PI3K. |
| Cellular Localization | Cell membrane, Cytoplasmic vesicle, Lysosome, Membrane |
| Calculated MW | 20~25 kDa |
| PTM | Lipoprotein, Methylation Prenylation |
Images (3) Click the Picture to Zoom In
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ARG43876 anti-RAB39A/B antibody WB image
Western blot: Hela, SH-SY5Y stained with ARG43876 anti-RAB39A/B antibody at 1:5000 dilution.
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ARG43876 anti-RAB39A/B antibody ICC/IF image
Immunofluorescence: U2OS cells stained with ARG43876 anti-RAB39A/B antibody at 1:500 dilution.
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ARG43876 anti-RAB39A/B antibody FACS image
Flow Cytometry: 293T cells stained with ARG43876 anti-RAB39A/B antibody (blue) at 1 μg/1x10^6 cells dilution.
