ARG52403

anti-Prox 1 antibody [5G10]

anti-Prox 1 antibody [5G10] for Immunohistochemistry and Human,Mouse,Rat,Chicken

Cell Biology and Cellular Response antibody; Gene Regulation antibody; Neuroscience antibody; Hippocampal Neurogenesis Marker antibody; Intermediate Progenitor Cells Marker antibody

Overview

Product Description Mouse Monoclonal antibody [5G10] recognizes Prox 1
Tested Reactivity Hu, Ms, Rat, Chk
Tested Application IHC
Host Mouse
Clonality Monoclonal
Clone 5G10
Isotype IgG1
Target Name Prox 1
Antigen Species Human
Immunogen Recombinant human Prox1 protein
Conjugation Un-conjugated
Alternate Names Prospero homeobox protein 1; Homeobox prospero-like protein PROX1; PROX-1

Application Instructions

Application Suggestion
Tested Application Dilution
IHC1:1000
Application Note Specifically labels prox1 in formalin-fixed, paraffin-embedded tissue.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Protein G purified
Buffer 10 mM HEPES (pH 7.5), 150 mM NaCl, 0.1 mg/ml BSA and 50% Glycerol
Stabilizer 0.1 mg/ml BSA, 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 19130 Mouse PROX1

GeneID: 395802 Chicken PROX1

GeneID: 5629 Human PROX1

Gene Symbol PROX1
Gene Full Name prospero homeobox 1
Background Prox1 (Prospero-related homeobox 1) is a divergent homeogene that regulates cell proliferation, fate determination and differentiation during vertebrate embryonic development. The protein is expressed in the developing lens and is also detected in embryonic brain, lung, liver and kidney; while in adult it is more abundant in heart and liver than in brain, skeletal muscle, kidney and pancreas (Chen et al., 2006). Prox1 is thought to play a fundamental role in early development of the CNS and may regulate gene expression and development of postmitotic undifferentiated young neurons (Misra et al., 2008)
Highlight Related Antibody Duos and Panels:
ARG30093 Hippocampal Neurogenesis Marker Antibody Duo (Prox1, Dcx)
Related products:
Prox1 antibodies; Prox1 Duos / Panels; Anti-Mouse IgG secondary antibodies;
Related news:
"Pro-aging factor" tied to immune-related molecule
Research Area Cell Biology and Cellular Response antibody; Gene Regulation antibody; Neuroscience antibody; Hippocampal Neurogenesis Marker antibody; Intermediate Progenitor Cells Marker antibody
Calculated MW 83 kDa

Images (1) Click the Picture to Zoom In

  • ARG52403 anti-Prox 1 antibody [5G10] IHC-P image

    Immunohistochemistry: Rat dentate gyrus showing specific immunolabeling of the prox1 protein stained with ARG52403 anti-Prox 1 antibody [5G10]

Clone References

Production of monoclonal antibodies against Prox1.

Chen X et al.
Hybridoma (Larchmt).,  (2006)

publication_link

 

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