ARG56496
anti-Prostaglandin E Synthase (cytosolic) antibody
anti-Prostaglandin E Synthase (cytosolic) antibody for Western blot and Human,Mouse,Sheep
Overview
| Product Description | Rabbit Polyclonal antibody recognizes Prostaglandin E Synthase (cytosolic) |
|---|---|
| Tested Reactivity | Hu, Ms, Sheep |
| Tested Application | WB |
| Specificity | This antibody does not react to Human recombinant mPGES. |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Prostaglandin E Synthase (cytosolic) |
| Antigen Species | Human |
| Immunogen | Synthetic peptide around an internal region of Human Prostaglandin E Synthase (cytosolic). |
| Conjugation | Un-conjugated |
| Alternate Names | EC 5.3.99.3; Progesterone receptor complex p23; TEBP; Hsp90 co-chaperone; P23; cPGES; Cytosolic prostaglandin E2 synthase; Prostaglandin E synthase 3; Telomerase-binding protein p23 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | TBS (pH 7.4), 0.02% Sodium azide, 50% Glycerol and 0.1% BSA. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol and 0.1% BSA |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | PTGES3 |
| Gene Full Name | prostaglandin E synthase 3 (cytosolic) |
| Function | Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway. [UniProt] |
| Calculated MW | 19 kDa |
Images (1) Click the Picture to Zoom In
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ARG56496 anti-Prostaglandin E Synthase (cytosolic) antibody WB image
Western blot: 1) 30 µg of Ram seminal vesicle microsomes, 2) Jurket (Mouse) cell lysate, 3) 30 µg of A549 cell lysate, 4) 0.04 µg of Recombinant Human cPGES, and 5) 0.10 µg of Recombinant Human cPGES stained with ARG56496 anti-Prostaglandin E Synthase (cytosolic) antibody.
