ARG63924
anti-Prostaglandin E Receptor EP1 antibody
anti-Prostaglandin E Receptor EP1 antibody for IHC-Formalin-fixed paraffin-embedded sections and Human
Signaling Transduction antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes Prostaglandin E Receptor EP1 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Prostaglandin E Receptor EP1 |
| Antigen Species | Human |
| Immunogen | C-DSRRRWGAHGPRS |
| Conjugation | Un-conjugated |
| Alternate Names | PGE2 receptor EP1 subtype; Prostanoid EP1 receptor; PGE receptor EP1 subtype; Prostaglandin E2 receptor EP1 subtype; EP1 |
Application Instructions
| Application Suggestion |
|
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|---|---|---|---|---|---|
| Application Note | IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P34995 Human Prostaglandin E2 receptor EP1 subtype |
|---|---|
| Background | The protein encoded by this gene is a member of the G protein-coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). Through a phosphatidylinositol-calcium second messenger system, G-Q proteins mediate this receptor's activity. Knockout studies in mice suggested a role of this receptor in mediating algesia and in regulation of blood pressure. Studies in mice also suggested that this gene may mediate adrenocorticotropic hormone response to bacterial endotoxin. [provided by RefSeq, Jul 2008] |
| Research Area | Signaling Transduction antibody |
| Calculated MW | 42 kDa |
| PTM | Phosphorylated. |
Images (2) Click the Picture to Zoom In
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ARG63924 anti-Prostaglandin E Receptor EP1 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human spleen tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG63924 anti-Prostaglandin E Receptor EP1 antibody at 5 µg/ml dilution followed by AP-staining.
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ARG63924 anti-Prostaglandin E Receptor EP1 antibody IHC image
Immunohistochemistry: paraffin-embedded Human Kidney (Steamed antigen retrieval with citrate buffer pH 6) stained with ARG63924 anti-Prostaglandin E Receptor EP1 antibody at 2 µg/ml dilution, followed by HRP-staining.
