ARG65199
anti-Pleiotrophin antibody
anti-Pleiotrophin antibody for Western blot and Human
Cancer antibody; Immune System antibody; Neuroscience antibody; Signaling Transduction antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes Pleiotrophin |
|---|---|
| Tested Reactivity | Hu |
| Predict Reactivity | Ms, Rat, Cow, Dog, Pig |
| Tested Application | WB |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Pleiotrophin |
| Antigen Species | Human |
| Immunogen | CGKLTKPKPQAESKK |
| Conjugation | Un-conjugated |
| Alternate Names | PTN; HBNF; Heparin-binding growth-associated molecule; Heparin-binding neurite outgrowth-promoting factor 1; HBGF8; HBNF-1; HBBM; Pleiotrophin; HBGF-8; OSF-1; Osteoblast-specific factor 1; Heparin-binding growth factor 8; Heparin-binding brain mitogen; NEGF1; HB-GAM; HARP |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | PTN |
| Gene Full Name | pleiotrophin |
| Function | Secreted growth factor that induces neurite outgrowth and which is mitogenic for fibroblasts, epithelial, and endothelial cells. Binds anaplastic lymphoma kinase (ALK) which induces MAPK pathway activation, an important step in the anti-apoptotic signaling of PTN and regulation of cell proliferation. [UniProt] |
| Research Area | Cancer antibody; Immune System antibody; Neuroscience antibody; Signaling Transduction antibody |
| Calculated MW | 19 kDa |
| PTM | Phosphorylated by NEK6. |
Images (1) Click the Picture to Zoom In
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ARG65199 anti-Pleiotrophin antibody WB image
Western Blot: 35 µg of Rat Brain lysate (protein in RIPA buffer) stained with ARG65199 anti-Pleiotrophin antibody at 0.3 µg/ml dilution.
