ARG64767
anti-Peroxiredoxin 1 antibody
anti-Peroxiredoxin 1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Cell Biology and Cellular Response antibody; Metabolism antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes Peroxiredoxin 1 |
|---|---|
| Tested Reactivity | Hu |
| Predict Reactivity | Ms, Rat, Cow, Dog, Pig |
| Tested Application | IHC-P, WB |
| Specificity | Reported variants represent identical protein (NP_002565.1, NP_859047.1, NP_859048.1). |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Peroxiredoxin 1 |
| Antigen Species | Human |
| Immunogen | C-SDPKRTIAQDYG |
| Conjugation | Un-conjugated |
| Alternate Names | EC 1.11.1.15; TDPX2; PAG; PRX1; MSP23; Natural killer cell-enhancing factor A; Peroxiredoxin-1; PRXI; NKEFA; PAGA; PAGB; Proliferation-associated gene protein; Thioredoxin peroxidase 2; NKEF-A; Thioredoxin-dependent peroxide reductase 2 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|---|---|
| Application Note | WB: Recommend incubate at RT for 1h. IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Background | This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. Four transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jan 2011] |
| Research Area | Cell Biology and Cellular Response antibody; Metabolism antibody |
| Calculated MW | 22 kDa |
| PTM | Phosphorylated on Thr-90 during the M-phase, which leads to a more than 80% decrease in enzymatic activity. |
Images (3) Click the Picture to Zoom In
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ARG64767 anti-Peroxiredoxin 1 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human thyroid gland tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG64767 anti-Peroxiredoxin 1 antibody at 2.5 µg/ml dilution followed by AP-staining.
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ARG64767 anti-Peroxiredoxin 1 antibody WB image
Western blot: 35 µg of HEK293 (A), A431 (B) and HepG2 (C) cell lysates (in RIPA buffer) stained with ARG64767 anti-Peroxiredoxin 1 antibody at 0.1 µg/ml dilution and incubated at RT for 1 hour.
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ARG64767 anti-Peroxiredoxin 1 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human placenta tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG64767 anti-Peroxiredoxin 1 antibody at 2.5 µg/ml dilution followed by AP-staining.
