ARG44000
anti-PSMD7 antibody
anti-PSMD7 antibody for ELISA,Flow cytometry,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes PSMD7 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | ELISA, FACS, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | PSMD7 |
| Antigen Species | Human |
| Immunogen | Human PSMD7 recombinant protein |
| Expression System | E.coli |
| Conjugation | Un-conjugated |
| Protein Full Name | 26S proteasome non-ATPase regulatory subunit 7 |
| Alternate Names | PSMD7; Proteasome 26S Subunit, Non-ATPase 7; MOV34; Rpn8; S12; P40; Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 7 (Mov34 Homolog); 26S Proteasome Non-ATPase Regulatory Subunit 7; 26S Proteasome Regulatory Subunit S12; Proteasome Subunit P40; Mov34 Homolog; Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 7; Moloney Leukemia Virus-34 Proviral Integration; 26S Proteasome Regulatory Subunit Rpn8; 26S Proteasome Regulatory Subunit RPN8; Mov34 Protein Homolog; MOV34L |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Buffer | 0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Bioinformation
| Database Links |
Swiss-port # P26516 Mouse 26S proteasome non-ATPase regulatory subunit 7 Swiss-port # P51665 Human 26S proteasome non-ATPase regulatory subunit 7 |
|---|---|
| Gene Symbol | PSMD7 |
| Gene Full Name | Proteasome 26S Subunit, Non-ATPase 7 |
| Background | The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 17. |
| Function | Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. |
| Cellular Localization | Proteasome |
| Calculated MW | 37 kDa |
| PTM | Acetylation, Isopeptide bond, Ubl conjugation |
Images (4) Click the Picture to Zoom In
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ARG44000 anti-PSMD7 antibody WB image
Western blot: Hela and K562 stained with ARG44000 anti-PSMD7 antibody at 0.5 μg/mL dilution.
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ARG44000 anti-PSMD7 antibody WB image FACS image
Flow Cytometry: MCF-7 cells stained with ARG44000 anti-PSMD7 antibody WB image (blue) at 1 μg/1x10^6 cells dilution.
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ARG44000 anti-PSMD7 antibody WB image
Western blot: Rat liver and RH35 stained with ARG44000 anti-PSMD7 antibody at 0.5 μg/mL dilution.
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ARG44000 anti-PSMD7 antibody WB image
Western blot: Mouse liver and NIH/3T3 stained with ARG44000 anti-PSMD7 antibody at 0.5 μg/mL dilution.
