ARG55476
anti-PSMA4 antibody
anti-PSMA4 antibody for ICC/IF,Immunoprecipitation,Western blot and Human,Mouse,Rat
Cell Biology and Cellular Response antibody
Overview
| Product Description | Rabbit Polyclonal antibody recognizes PSMA4 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | ICC/IF, IP, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | PSMA4 |
| Antigen Species | Human |
| Immunogen | Recombinant protein of Human PSMA4 |
| Conjugation | Un-conjugated |
| Alternate Names | Proteasome component C9; PSC9; Proteasome subunit alpha type-4; HC9; Proteasome subunit L; HsT17706; Multicatalytic endopeptidase complex subunit C9; Macropain subunit C9; EC 3.4.25.1 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Positive Control | Jurkat, Mouse liver and PC-12 | ||||||||
| Observed Size | ~ 30 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | PSMA4 |
| Gene Full Name | proteasome (prosome, macropain) subunit, alpha type, 4 |
| Background | The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| Function | The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. [UniProt] |
| Research Area | Cell Biology and Cellular Response antibody |
| Calculated MW | 29 kDa |
Images (3) Click the Picture to Zoom In
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ARG55476 anti-PSMA4 antibody ICC/IF image
Immunofluorescence: U2OS cells stained with ARG55476 anti-PSMA4 antibody.
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ARG55476 anti-PSMA4 antibody WB image
Western blot: Jurkat cell lysate stained with ARG55476 anti-PSMA4 antibody.
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ARG55476 anti-PSMA4 antibody WB image
Western blot: Mouse liver and PC-12 cell lysates stained with ARG55476 anti-PSMA4 antibody.
