ARG64959

anti-PSD95 antibody

anti-PSD95 antibody for Western blot and Rat

Neuroscience antibody

Overview

Product Description Goat Polyclonal antibody recognizes DLG4 / PSD95
Tested Reactivity Rat
Predict Reactivity Hu, Ms, Cow, Dog
Tested Application WB
Specificity This antibody is expected to recognize both reported isoforms (NP_001356.1; NP_001122299.1)
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name PSD95
Antigen Species Human
Immunogen C-EEQARKAFDRATK
Conjugation Un-conjugated
Alternate Names Postsynaptic density protein 95; SAP90; PSD-95; Synapse-associated protein 90; PSD95; SAP-90; Disks large homolog 4

Application Instructions

Application Suggestion
Tested Application Dilution
WB0.3 - 1 µg/ml
Application Note WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 29495 Rat DLG4

Swiss-port # P31016 Rat Disks large homolog 4

Background This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. It heteromultimerizes with another MAGUK protein, DLG2, and is recruited into NMDA receptor and potassium channel clusters. These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Research Area Neuroscience antibody
Calculated MW 80 kDa
PTM Palmitoylation of isoform 1 is required for targeting to postsynaptic density.

Images (1) Click the Picture to Zoom In

  • ARG64959 anti-DLG4 / PSD95 antibody WB image

    Western Blot: Rat Brain lysate (35 µg protein in RIPA buffer) stained with ARG64959 anti-DLG4 / PSD95 antibody at 0.3 µg/ml dilution.