ARG63090

anti-PSA antibody [A67-B/E3] (Biotin)

anti-PSA antibody [A67-B/E3] (Biotin) for ELISA,Western blot and Human

Cancer antibody; Controls and Markers antibody; Neuroscience antibody; Signaling Transduction antibody

Overview

Product Description Biotin-conjugated Mouse Monoclonal antibody [A67-B/E3] recognizes PSA
Tested Reactivity Hu
Tested Application ELISA, WB
Specificity The clone A67-B/E3 reacts with prostate-specific antigen (PSA),a protein produced by normal prostate cells. The highest amounts of PSA are found in the seminal fluid.
Host Mouse
Clonality Monoclonal
Clone A67-B/E3
Isotype IgG1
Target Name PSA
Antigen Species Human
Immunogen 30 KDa protein fraction prepared from human seminal plasma
Conjugation Biotin
Alternate Names Prostate-specific antigen; Gamma-seminoprotein; APS; PSA; EC 3.4.21.77; Kallikrein-3; P-30 antigen; Semenogelase; hK3; Seminin; KLK2A1

Application Instructions

Application Suggestion
Tested Application Dilution
ELISAAssay-dependent
WB1:1000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Note The purified antibody is conjugated with Biotin-LC-NHS under optimum conditions. The reagent is free of unconjugated biotin.
Buffer PBS (pH 7.4) and 15 mM Sodium azide
Preservative 15 mM Sodium azide
Concentration 1 mg/ml
Storage Instruction Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 354 Human KLK3

Swiss-port # P07288 Human Prostate-specific antigen

Gene Symbol KLK3
Gene Full Name kallikrein-related peptidase 3
Background Prostate-specific antigen (PSA) is a protein produced by normal prostate cells. This enzyme participates in the dissolution of the seminal fluid coagulum and plays an important role in fertility. The highest amounts of PSA are found in the seminal fluid; some PSA escapes the prostate and can be found in the serum. This serum component has been used to track the response to therapy in men with prostate cancer.
ISOBM TD-3 PSA Workshop code: 207
Function Hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum. [UniProt]
Research Area Cancer antibody; Controls and Markers antibody; Neuroscience antibody; Signaling Transduction antibody
Calculated MW 29 kDa

Images (1) Click the Picture to Zoom In

  • ARG63090 anti-PSA antibody [A67-B/E3] (Biotin) ELISA image

    ELISA: Detection of PSA with ARG63090 anti-PSA antibody [A67-B/E3] (Biotin). Compared with ARG65323 Mouse IgG1 Kappa Isotype Control antibody [MOPC-21].

Clone References

Characterization of a novel androgen receptor mutation in a relapsed CWR22 prostate cancer xenograft and cell line.

WB / Human

Tepper CG et al.
Cancer Res.,  (2002)

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