ARG63091
anti-PSA antibody [A67-B/E3]
anti-PSA antibody [A67-B/E3] for ELISA,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Cancer antibody; Controls and Markers antibody; Neuroscience antibody; Signaling Transduction antibody
Overview
| Product Description | Mouse Monoclonal antibody [A67-B/E3] recognizes PSA |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA, IHC-P, WB |
| Specificity | The clone A67-B/E3 reacts with prostate-specific antigen (PSA),a protein produced by normal prostate cells. The highest amounts of PSA are found in the seminal fluid. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | A67-B/E3 |
| Isotype | IgG1 |
| Target Name | PSA |
| Antigen Species | Human |
| Immunogen | 30 KDa protein fraction prepared from human seminal plasma |
| Conjugation | Un-conjugated |
| Alternate Names | Prostate-specific antigen; Gamma-seminoprotein; APS; PSA; EC 3.4.21.77; Kallikrein-3; P-30 antigen; Semenogelase; hK3; Seminin; KLK2A1 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Positive Control | WB: Seminal plasma |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from ascites by precipitation methods. |
| Purity | > 95% (by SDS-PAGE) |
| Buffer | PBS (pH 7.4) and 15 mM Sodium azide |
| Preservative | 15 mM Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | KLK3 |
| Gene Full Name | kallikrein-related peptidase 3 |
| Background | Prostate-specific antigen (PSA) is a protein produced by normal prostate cells. This enzyme participates in the dissolution of the seminal fluid coagulum and plays an important role in fertility. The highest amounts of PSA are found in the seminal fluid; some PSA escapes the prostate and can be found in the serum. This serum component has been used to track the response to therapy in men with prostate cancer. ISOBM TD-3 PSA Workshop code: 207 |
| Function | Hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum. [UniProt] |
| Research Area | Cancer antibody; Controls and Markers antibody; Neuroscience antibody; Signaling Transduction antibody |
| Calculated MW | 29 kDa |
Images (3) Click the Picture to Zoom In
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ARG63091 anti-PSA antibody [A67-B/E3] IHC-P image
Immunohistochemistry: Paraffin-embedded Human prostate tissue stained with ARG63091 anti-PSA antibody [A67-B/E3] at 10 µg/ml dilution.
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ARG63091 anti-PSA antibody [A67-B/E3] IHC-P image
Immunohistochemistry: Prostate paraffin section stained with ARG63091 anti-PSA antibody [A67-B/E3].
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ARG63091 anti-PSA antibody [A67-B/E3] WB image
Western blot: Human seminal plasma stained with ARG63091 anti-PSA antibody [A67-B/E3] at 5 µg/ml dilution, under reducing condition.
Clone References
Characterization of a novel androgen receptor mutation in a relapsed CWR22 prostate cancer xenograft and cell line.
WB / Human
