ARG59712
anti-PRELP antibody
anti-PRELP antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes PRELP |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | FACS, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | PRELP |
| Antigen Species | Human |
| Immunogen | KLH-conjugated synthetic peptide between aa. 257-286 of Human PRELP. |
| Conjugation | Un-conjugated |
| Alternate Names | MST161; SLRR2A; Prolargin; Proline-arginine-rich end leucine-rich repeat protein; MSTP161 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Positive Control | Y79 | ||||||||
| Observed Size | 43 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Saturated Ammonium Sulfate precipitation followed by dialysis against PBS. |
| Buffer | PBS and 0.09% (W/V) Sodium azide. |
| Preservative | 0.09% (W/V) Sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | PRELP |
| Gene Full Name | proline/arginine-rich end leucine-rich repeat protein |
| Background | The protein encoded by this gene is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008] |
| Function | May anchor basement membranes to the underlying connective tissue. [UniProt] |
| Cellular Localization | Secreted, extracellular space, extracellular matrix. [UniProt] |
| Calculated MW | 44 kDa |
Images (3) Click the Picture to Zoom In
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ARG59712 anti-PRELP antibody IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded Human hepatocarcinoma stained with ARG59712 anti-PRELP antibody.
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ARG59712 anti-PRELP antibody WB image
Western blot: 35 µg of Y79 cell lysate stained with ARG59712 anti-PRELP antibody.
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ARG59712 anti-PRELP antibody FACS image
Flow Cytometry: WiDr cells stained with ARG59712 anti-PRELP antibody (bottom histogram) or without primary antibody as control (top histogram), followed by incubation with FITC-labelled secondary antibody.
