ARG41189
anti-PPP4R1 antibody
anti-PPP4R1 antibody for Immunoprecipitation,Western blot and Human,Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes PPP4R1 |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | IP, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | PPP4R1 |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 324-647 of Human PPP4R1 (NP_001035847.1). |
| Conjugation | Un-conjugated |
| Alternate Names | Serine/threonine-protein phosphatase 4 regulatory subunit 1; PP4R1; MEG1; PP4(Rmeg) |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Positive Control | SKOV3 | ||||||
| Observed Size | 130 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q8K2V1 Mouse Serine/threonine-protein phosphatase 4 regulatory subunit 1 Swiss-port # Q8TF05 Human Serine/threonine-protein phosphatase 4 regulatory subunit 1 |
|---|---|
| Gene Symbol | PPP4R1 |
| Gene Full Name | protein phosphatase 4, regulatory subunit 1 |
| Background | This gene encodes one of several alternate regulatory subunits of serine/threonine protein phosphatase 4 (PP4). The protein features multiple HEAT repeats. This protein forms a complex with PP4RC. This complex may have a distinct role from other PP4 complexes, including regulation of HDAC3 (Zhang et al., PMID: 15805470). There is also a transcribed pseudogene on chromosome 20. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012] |
| Function | Regulatory subunit of serine/threonine-protein phosphatase 4. May play a role in regulation of cell division in renal glomeruli. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3. [UniProt] |
| Calculated MW | 107 kDa |
Images (2) Click the Picture to Zoom In
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ARG41189 anti-PPP4R1 antibody WB image
Western blot: 25 µg of SKOV3 cell lysate stained with ARG41189 anti-PPP4R1 antibody at 1:1000 dilution.
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ARG41189 anti-PPP4R1 antibody IP image
Immunoprecipitation: 200 µg extracts of 293T cells were immunoprecipitated and stained with ARG41189 anti-PPP4R1 antibody at 1:1000 dilution.
