ARG43956
anti-PPP1R11 antibody
anti-PPP1R11 antibody for ELISA,Flow cytometry,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes PPP1R11 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | ELISA, FACS, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | PPP1R11 |
| Antigen Species | Human |
| Immunogen | Human PPP1R11 recombinant protein |
| Expression System | E.coli |
| Conjugation | Un-conjugated |
| Protein Full Name | E3 ubiquitin-protein ligase PPP1R11 |
| Alternate Names | PPP1R11; Protein Phosphatase 1 Regulatory Inhibitor Subunit 11; HCGV; CFAP255; HCG-V; TCTE5; Protein Phosphatase 1 Regulatory Subunit 11; Hemochromatosis Candidate Gene V Protein; E3 Ubiquitin-Protein Ligase PPP1R11; Protein Phosphatase Inhibitor 3; Tctex5; HCG V; Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 11; T-Complex-Associated-Testis-Expressed 5; Inhibitor-3; EC 2.3.2.27; TCTEX5; IPP3 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Buffer | 0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | PPP1R11 |
| Gene Full Name | Protein Phosphatase 1 Regulatory Inhibitor Subunit 11 |
| Background | This gene encodes a specific inhibitor of protein phosphatase-1 (PP1) with a differential sensitivity toward the metal-independent and metal-dependent forms of PP1. The gene is located within the major histocompatibility complex class I region on chromosome 6. |
| Function | Atypical E3 ubiquitin-protein ligase which ubiquitinates TLR2 at 'Lys-754' leading to its degradation by the proteasome. Plays a role in regulating inflammatory cytokine release and gram-positive bacterial clearance by functioning, in part, through the ubiquitination and degradation of TLR2. |
| Cellular Localization | Cytoplasm, Nucleus |
| Calculated MW | 14 kDa |
| PTM | Acetylation, Phosphoprotein, Ubl conjugation |
Images (4) Click the Picture to Zoom In
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ARG43956 anti-PPP1R11 antibody WB image
Western blot: HepG2 and HeLa stained with ARG43956 anti-PPP1R11 antibody at 0.5 μg/mL dilution.
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ARG43956 anti-PPP1R11 antibody FACS image
Flow Cytometry: MCF-7 cells stained with ARG43956 anti-PPP1R11 antibody (blue) at 1 μg/1x10^6 cells dilution.
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ARG43956 anti-PPP1R11 antibody WB image
Western blot: Rat testis and Rat liver stained with ARG43956 anti-PPP1R11 antibody at 0.5 μg/mL dilution.
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ARG43956 anti-PPP1R11 antibody WB image
Western blot: Mouse testis stained with ARG43956 anti-PPP1R11 antibody at 0.5 μg/mL dilution.
