ARG43924
anti-POLR1C antibody
anti-POLR1C antibody for ELISA,Flow cytometry,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes POLR1C |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA, FACS, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Target Name | POLR1C |
| Antigen Species | Human |
| Immunogen | Human POLR1C recombinant protein |
| Expression System | E.coli |
| Conjugation | Un-conjugated |
| Protein Full Name | DNA-directed RNA polymerases I and III subunit RPAC1 |
| Alternate Names | POLR1C; RNA Polymerase I And III Subunit C; RPA40; RPA39; RPC40; AC40; RPAC1; RPA5; DNA-Directed RNA Polymerases I And III 40 KDa Polypeptide; DNA-Directed RNA Polymerases I And III Subunit RPAC1; Polymerase (RNA) I Polypeptide C, 30kDa; DNA-Directed RNA Polymerase I Subunit C; RNA Polymerases I And III Subunit AC1; RNA Polymerase I Subunit C; Polymerase (RNA) I Subunit C; POLR1E; HLD11; TC |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Buffer | 0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Bioinformation
| Database Links |
Swiss-port # O15160 Human DNA-directed RNA polymerases I and III subunit RPAC1 |
|---|---|
| Gene Symbol | POLR1C |
| Gene Full Name | RNA Polymerase I And III Subunit C |
| Background | The protein encoded by this gene is a subunit of both RNA polymerase I and RNA polymerase III complexes. The encoded protein is part of the Pol core element. Mutations in this gene have been associated with Treacher Collins syndrome (TCS) and hypomyelinating leukodystrophy 11. Alternative splicing results in multiple transcript variants. |
| Function | DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively. RPAC1 is part of the Pol core element with the central large cleft and probably a clamp element that moves to open and close the cleft. |
| Cellular Localization | DNA-directed RNA polymerase, Nucleus |
| Calculated MW | 39 kDa |
| PTM | Acetylation, Phosphoprotein |
Images (2) Click the Picture to Zoom In
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ARG43924 anti-POLR1C antibody WB image
Western blot: 293T, K562 and RT4 stained withARG43924 anti-POLR1C antibody at 0.5 μg/mL dilution.
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ARG43924 anti-POLR1C antibody FACS image
Flow Cytometry: RT4 cells stained withARG43924 anti-POLR1C antibody (blue) at 1 μg/1x10^6 cells dilution.
