Overview

Product Description	Rabbit Polyclonal antibody recognizes POLD2
Tested Reactivity	Hu, Ms, Rat
Tested Application	WB
Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Target Name	POLD2
Antigen Species	Human
Immunogen	Recombinant protein of human POLD2
Conjugation	Un-conjugated
Alternate Names	DNA polymerase delta subunit 2; DNA polymerase delta subunit p50; EC 2.7.7.7

Application Instructions

Predict Reactivity Note	Rat
Application Suggestion	Tested Application Dilution WB 1:500 - 1:2000
Application Note	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control	HL-60
Observed Size	~ 51 kDa

Properties

Form	Liquid
Purification	Affinity purification with immunogen.
Buffer	PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
Preservative	0.02% Sodium azide
Stabilizer	50% Glycerol
Storage Instruction	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note	For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links	GeneID: 18972 Mouse POLD2 GeneID: 289758 Rat POLD2 GeneID: 5425 Human POLD2 Swiss-port # O35654 Mouse DNA polymerase delta subunit 2 Swiss-port # P49005 Human DNA polymerase delta subunit 2 Swiss-port # Q6AXY4 Rat DNA polymerase delta subunit 2 More
Gene Symbol	POLD2
Gene Full Name	polymerase (DNA directed), delta 2, accessory subunit
Background	This gene encodes the 50-kDa catalytic subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein is required for the stimulation of DNA polymerase delta activity by the processivity cofactor proliferating cell nuclear antigen (PCNA). Expression of this gene may be a marker for ovarian carcinomas. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Mar 2012]
Function	The function of the small subunit is not yet clear. [UniProt]
Calculated MW	51 kDa

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