ARG43895
anti-PNPLA6 / NTE antibody
anti-PNPLA6 / NTE antibody for ELISA,Flow cytometry,ICC/IF,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes PNPLA6 / NTE |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA, FACS, ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Target Name | PNPLA6 / NTE |
| Antigen Species | Human |
| Immunogen | Human PNPLA6 / NTE recombinant protein |
| Expression System | E.coli |
| Conjugation | Un-conjugated |
| Protein Full Name | Patatin-like phospholipase domain-containing protein 6 |
| Alternate Names | PNPLA6; Patatin Like Phospholipase Domain Containing 6; NTE; Neuropathy Target Esterase; IPLA2delta; SPG39; Sws; Patatin-Like Phospholipase Domain-Containing Protein 6; EC 3.1.1.5; Patatin-Like Phospholipase Domain Containing 6; NTEMND; BNHS; LNMS; OMCS |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Buffer | 0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | PNPLA6 |
| Gene Full Name | Patatin Like Phospholipase Domain Containing 6 |
| Background | This gene encodes a phospholipase that deacetylates intracellular phosphatidylcholine to produce glycerophosphocholine. It is thought to function in neurite outgrowth and process elongation during neuronal differentiation. The protein is anchored to the cytoplasmic face of the endoplasmic reticulum in both neurons and non-neuronal cells. Mutations in this gene result in autosomal recessive spastic paraplegia, and the protein is the target for neurodegeneration induced by organophosphorus compounds and chemical warfare agents. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Function | Phospholipase B that deacylates intracellular phosphatidylcholine (PtdCho), generating glycerophosphocholine (GroPtdCho). This deacylation occurs at both sn-2 and sn-1 positions of PtdCho. Catalyzes the hydrolysis of several naturally occurring membrane-associated lipids. |
| Cellular Localization | Membrane |
| Calculated MW | 151 kDa |
| PTM | Glycoprotein, Phosphoprotein |
Images (4) Click the Picture to Zoom In
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ARG43895 anti-PNPLA6 / NTE antibody ICC/IF image
Immunofluorescence: U2OS cells stained with ARG43895 anti-PNPLA6 / NTE antibody at 5 μg/ml dilution.
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ARG43895 anti-PNPLA6 / NTE antibody WB image
Western blot: 293T and SH-SY5Y stained with ARG43895 anti-PNPLA6 / NTE antibody at 0.5 μg/mL dilution.
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ARG43895 anti-PNPLA6 / NTE antibody FACS image
Flow Cytometry: SiHa cells stained with ARG43895 anti-PNPLA6 / NTE antibody (blue) at 1 μg/1x10^6 cells dilution.
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ARG43895 anti-PNPLA6 / NTE antibody WB image
Western blot: HeLa stained with ARG43895 anti-PNPLA6 / NTE antibody at 0.5 μg/mL dilution.
