ARG44534
anti-PMPCA / INPP5E antibody
anti-PMPCA / INPP5E antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes PMPCA / INPP5E |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | PMPCA / INPP5E |
| Antigen Species | Human |
| Immunogen | Human PMPCA / INPP5E recombinant protein. |
| Conjugation | Un-conjugated |
| Alternate Names | PMPCA; Peptidase, Mitochondrial Processing Subunit Alpha; Alpha-MPP; KIAA0123; INPP5E; MAS2; Mitochondrial-Processing Peptidase Subunit Alpha; Inositol Polyphosphate-5-Phosphatase, 72 KD; Cerebellar Ataxia 1 (Autosomal Recessive); Inactive Zinc Metalloprotease Alpha; SCAR2; CLA1; P-55; Mitochondrial Matrix Processing Protease, Alpha Subunit; Peptidase, Mitochondrial Processing Alpha Subunit; Spinocerebellar Ataxia, Autosomal Recessive 2; Peptidase (Mitochondrial Processing) Alpha; Cerebellar Ataxia-1; EC 3.4.24.64; CPD3; MPPA |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q10713 Human Mitochondrial-processing peptidase subunit alpha Swiss-port # Q9DC61 Mouse Mitochondrial-processing peptidase subunit alpha |
|---|---|
| Gene Symbol | PMPCA |
| Gene Full Name | Peptidase, Mitochondrial Processing Subunit Alpha |
| Background | The protein encoded by this gene is found in the mitochondrion, where it represents the alpha subunit of a proteolytic heterodimer. This heterodimer is responsible for cleaving the transit peptide from nuclear-encoded mitochondrial proteins. Defects in this gene are a cause of spinocerebellar ataxia, autosomal recessive 2. |
| Function | Substrate recognition and binding subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins. |
| Cellular Localization | Membrane, Mitochondrion, Mitochondrion inner membrane |
| Calculated MW | 58 kDa |
| PTM | Acetylation |
Images (8) Click the Picture to Zoom In
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ARG44534 anti-PMPCA / INPP5E antibody IHC-P image
Immunohistochemistry: Human renal cancer stained with ARG44534 anti-PMPCA / INPP5E antibody at 2 μg/ml dilution.
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ARG44534 anti-PMPCA / INPP5E antibody ICC/IF image
Immunofluorescence: HEP3B stained with ARG44534 anti-PMPCA / INPP5E antibody at 5 μg/ml dilution.
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ARG44534 anti-PMPCA / INPP5E antibody WB image
Western blot: MCF-7, A549 and T-47D stained with ARG44534 anti-PMPCA / INPP5E antibody at 0.5 μg/mL dilution.
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ARG44534 anti-PMPCA / INPP5E antibody FACS image
Flow Cytometry: U937 stained with ARG44534 anti-PMPCA / INPP5E antibody at 1 μg/10^6 cells dilution.
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ARG44534 anti-PMPCA / INPP5E antibody IHC-P image
Immunohistochemistry: Rat brain stained with ARG44534 anti-PMPCA / INPP5E antibody at 2 μg/ml dilution.
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ARG44534 anti-PMPCA / INPP5E antibody WB image
Western blot: Rat liver stained with ARG44534 anti-PMPCA / INPP5E antibody at 0.5 μg/mL dilution.
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ARG44534 anti-PMPCA / INPP5E antibody WB image
Western blot: Mouse liver stained with ARG44534 anti-PMPCA / INPP5E antibody at 0.5 μg/mL dilution.
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ARG44534 anti-PMPCA / INPP5E antibody IHC-P image
Immunohistochemistry: Human tonsil stained with ARG44534 anti-PMPCA / INPP5E antibody at 2 μg/ml dilution.
