ARG40792
anti-PLAGL1 / ZAC antibody
anti-PLAGL1 / ZAC antibody for Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes PLAGL1 / ZAC |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | PLAGL1 / ZAC |
| Antigen Species | Human |
| Immunogen | KLH conjugated synthetic peptide between aa. 112-146 of Human PLAGL1 / ZAC. |
| Conjugation | Un-conjugated |
| Alternate Names | LOT-1; LOT1; ZAC; Lost on transformation 1; Pleiomorphic adenoma-like protein 1; Zinc finger protein PLAGL1; Tumor suppressor ZAC; ZAC1 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A and immunogen peptide. |
| Buffer | PBS and 0.09% (W/V) Sodium azide. |
| Preservative | 0.09% (W/V) Sodium azide. |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | PLAGL1 |
| Gene Full Name | pleiomorphic adenoma gene-like 1 |
| Background | This gene encodes a C2H2 zinc finger protein with transactivation and DNA-binding activities. It has been shown to have anti-proliferative properties, and thus thought to function as a tumor suppressor. In addition, overexpression of this gene during fetal development is believed to underlie the rare disorder, transient neonatal diabetes mellitus (TNDM). This gene is imprinted, with preferential expression of the paternal allele in many tissues, however, biallelic expression has been noted in peripheral blood leucocytes. A recent study reports that tissue-specific imprinting results from variable utilization of monoallelic and biallelic promoters. Many transcript variants differing in the 5' UTR and encoding two different isoforms, have been found for this gene. [provided by RefSeq, Oct 2010] |
| Function | Shows weak transcriptional activatory activity. Transcriptional regulator of the type 1 receptor for pituitary adenylate cyclase-activating polypeptide. [UniProt] |
| Cellular Localization | Nucleus. [UniProt] |
| Calculated MW | 51 kDa |
Images (1) Click the Picture to Zoom In
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ARG40792 anti-PLAGL1 / ZAC antibody WB image
Western blot: 20 µg of HeLa cell lysate stained with ARG40792 anti-PLAGL1 / ZAC antibody at 1:2000 dilution.
