ARG64548

anti-PGRPS antibody

anti-PGRPS antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human

Cell Biology and Cellular Response antibody; Cell Death antibody; Immune System antibody; Microbiology and Infectious Disease antibody; Neuroscience antibody

Overview

Product Description Goat Polyclonal antibody recognizes PGRPS
Tested Reactivity Hu
Predict Reactivity Dog
Tested Application IHC-P, WB
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name PGRPS
Antigen Species Human
Immunogen C-PGNQLYHLIQN
Conjugation Un-conjugated
Alternate Names TAG7; PGRP; PGRPS; PGLYRP; Peptidoglycan recognition protein short; TNFSF3L; PGRP-S; Peptidoglycan recognition protein 1

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P3 - 6 µg/ml
WB0.3 - 1 µg/ml
Application Note IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0).
WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 8993 Human PGLYRP1

Swiss-port # O75594 Human Peptidoglycan recognition protein 1

Gene Symbol PGLYRP1
Gene Full Name peptidoglycan recognition protein 1
Function Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria, and has bacteriostatic activity towards Gram-negative bacteria. Plays a role in innate immunity. [UniProt]
Research Area Cell Biology and Cellular Response antibody; Cell Death antibody; Immune System antibody; Microbiology and Infectious Disease antibody; Neuroscience antibody
Calculated MW 22 kDa
PTM N-glycosylated. N-glycosylation is required for bactericidal activity.

Images (2) Click the Picture to Zoom In

  • ARG64548 anti-PGRPS antibody WB image

    Western blot: Jurkat lysate (35 µg protein in RIPA buffer) stained with ARG64548 anti-PGRPS antibody at 0.3 µg/ml dilution.

  • ARG64548 anti-PGRPS antibody IHC-P image

    Immunohistochemistry: Paraffin embedded Human Spleen. (Steamed antigen retrieval with citrate buffer pH 6) stained with ARG64548 anti-PGRPS antibody at 3.8 µg/ml dilution followed by AP-staining.