ARG40799
anti-PFDN5 antibody
anti-PFDN5 antibody for ICC/IF,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes PFDN5 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | PFDN5 |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 1-154 of Human PFDN5 (NP_002615.2). |
| Conjugation | Un-conjugated |
| Alternate Names | PFD5; C-Myc-binding protein Mm-1; MM1; MM-1; Myc modulator 1; Prefoldin subunit 5 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Positive Control | Raji | ||||||
| Observed Size | 15 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | PFDN5 |
| Gene Full Name | prefoldin subunit 5 |
| Background | This gene encodes a member of the prefoldin alpha subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils. The encoded protein may also repress the transcriptional activity of the proto-oncogene c-Myc. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008] |
| Function | Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins. Represses the transcriptional activity of MYC. [UniProt] |
| Cellular Localization | Isoform 1: Nucleus. Isoform 2: Cytoplasm. Isoform 3: Nucleus. [UniProt] |
| Calculated MW | 17 kDa |
Images (1) Click the Picture to Zoom In
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ARG40799 anti-PFDN5 antibody WB image
Western blot: 25 µg of Raji cell lysate stained with ARG40799 anti-PFDN5 antibody at 1:3000 dilution.
