ARG52391
anti-PEBP antibody
anti-PEBP antibody for Western blot and Rat
Cancer antibody; Cell Biology and Cellular Response antibody; Gene Regulation antibody; Neuroscience antibody
Overview
| Product Description | Rabbit Polyclonal antibody recognizes PEBP |
|---|---|
| Tested Reactivity | Rat |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | PEBP |
| Antigen Species | Rat |
| Immunogen | Purified native rat PEBP |
| Conjugation | Un-conjugated |
| Alternate Names | PEBP; PBP; HCNP; HEL-S-34; RKIP; Prostatic-binding protein; HCNPpp; Phosphatidylethanolamine-binding protein 1; Raf kinase inhibitor protein; Neuropolypeptide h3; HEL-210; PEBP-1 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | Specific for the ~ 22k PEBP protein in Western blots * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Neat Serum |
| Buffer | Neat serum |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P31044 Rat Phosphatidylethanolamine-binding protein 1 |
|---|---|
| Gene Symbol | PEBP1 |
| Gene Full Name | phosphatidylethanolamine binding protein 1 |
| Background | Phosphatidylethanolamine binding protein (PEBP), also known as Raf kinase inhibitory protein (RKIP) is a highly conserved multifunctional protein that modulates the Raf/MAPK signaling cascade and has been implicated as a suppressor of metastatic cancer (Trakul N et al., 2005). PEBP has been shown to not only inhibit cell proliferation but also to induce differentiation of human keratinocytes (Yamazaki et al., 2004). Dysregulation of calpain activity results in cellular degeneration in conditions such as Alzheimer’s disease and recently PEBP has been identified as a potential in vivo calpain substrate (Chen at al., 2006). |
| Research Area | Cancer antibody; Cell Biology and Cellular Response antibody; Gene Regulation antibody; Neuroscience antibody |
| Calculated MW | 21 kDa |
Images (1) Click the Picture to Zoom In
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ARG52391 anti-PEBP antibody WB image
Western blot: rat brain lysate stained with ARG52391 anti-PEBP antibody showing the specific immunolabeling of the ~ 22k PEBP protein.
