ARG64440
anti-PAM / PAL antibody
anti-PAM / PAL antibody for Western blot and Human
Neuroscience antibody; Signaling Transduction antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes PAM / PAL |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Specificity | This antibody is expected to recognise all reported isoforms (NP_000910.2; NP_620121.1; NP_620176.1 and NP_620177.1). |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | PAM / PAL |
| Antigen Species | Human |
| Immunogen | C-DQEKEDDGSESEE |
| Conjugation | Un-conjugated |
| Alternate Names | Peptidylamidoglycolate lyase; PHM; EC 4.3.2.5; Peptidyl-glycine alpha-amidating monooxygenase; EC 1.14.17.3; PAL; PAM |
Application Instructions
| Application Suggestion |
|
||||
|---|---|---|---|---|---|
| Application Note | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P19021 Human Peptidyl-glycine alpha-amidating monooxygenase |
|---|---|
| Background | This gene encodes a multifunctional protein. It has two enzymatically active domains with catalytic activities - peptidylglycine alpha-hydroxylating monooxygenase (PHM) and peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL). These catalytic domains work sequentially to catalyze neuroendocrine peptides to active alpha-amidated products. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene but some of their full length sequences are not yet known. [provided by RefSeq, Jul 2008] |
| Research Area | Neuroscience antibody; Signaling Transduction antibody |
| Calculated MW | 108 kDa |
Images (1) Click the Picture to Zoom In
-
ARG64440 anti-PAM / PAL antibody WB image
Western Blot: Human Kidney lysate (35 µg protein in RIPA buffer) stained with ARG64440 anti-PAM / PAL antibody at 1 µg/ml dilution.
