ARG66003
anti-Oncostatin M antibody (Biotin)
anti-Oncostatin M antibody (Biotin) for ELISA and Human
Overview
| Product Description | Biotin-conjugated Rabbit Polyclonal antibody recognizes Oncostatin M |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Oncostatin M |
| Antigen Species | Human |
| Immunogen | E. coli derived recombinant Human Oncostatin M. (AAIGSCSKEY RVLLGQLQKQ TDLMQDTSRL LDPYIRIQGL DVPKLREHCR ERPGAFPSEE TLRGLGRRGF LQTLNATLGC VLHRLADLEQ RLPKAQDLER SGLNIEDLEK LQMARPNILG LRNNIYCMAQ LLDNSDTAEP TKAGRGASQP PTPTPASDAF QRKLEGCRFL HGYHRFMHSV GRVFSKWGES PNRSRRHSPH QALRKGVRRT RPSRKGKRLM TRGQLPR) |
| Conjugation | Biotin |
| Alternate Names | OSM; Oncostatin-M |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified by affinity chromatography. |
| Buffer | PBS (pH 7.2) |
| Concentration | 1 mg/ml |
| Storage Instruction | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | OSM |
| Gene Full Name | oncostatin M |
| Background | Oncostatin M is a member of a cytokine family that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6. This gene encodes a growth regulator which inhibits the proliferation of a number of tumor cell lines. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. [provided by RefSeq, Jul 2008] |
| Function | Growth regulator. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIPR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration (By similarity). [UniProt] |
| Calculated MW | 28 kDa |
| PTM | Propeptide processing is not important for receptor binding activity but may be important growth-inhibitory activity. |
Images (2) Click the Picture to Zoom In
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ARG66003 anti-Oncostatin M antibody (Biotin) standard curve image
Direct ELISA: ARG66003 anti-Oncostatin M antibody (Biotin) at 0.25 - 1.0 µg/ml results of a typical standard run with optical density reading at 405 - 650 nm.
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ARG66003 anti-Oncostatin M antibody (Biotin) standard curve image
Sandwich ELISA: ARG66003 anti-Oncostatin M antibody (Biotin) as a detection antibody at 0.25 - 1.0 µg/ml combined with ARG66002 anti-Oncostatin M antibody as a capture antibody. Results of a typical standard run with optical density reading at 405 - 650 nm.
