ARG63387

anti-OSBPL2 / ORP2 antibody

anti-OSBPL2 / ORP2 antibody for Western blot and Human

Cell Biology and Cellular Response antibody; Metabolism antibody; Signaling Transduction antibody

Overview

Product Description Goat Polyclonal antibody recognizes OSBPL2 / ORP2
Tested Reactivity Hu
Predict Reactivity Ms, Rat
Tested Application WB
Specificity This antibody is expected to recognise both reported isoforms (represented by NP_055650.1 and NP_653081.1)
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name OSBPL2 / ORP2
Antigen Species Human
Immunogen YFERNFSDCPDIY
Conjugation Un-conjugated
Alternate Names Oxysterol-binding protein-related protein 2; ORP-2; DNFA67; ORP2; OSBP-related protein 2; DFNA67

Application Instructions

Application Suggestion
Tested Application Dilution
WB1 - 2 µg/ml
Application Note WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 9885 Human OSBPL2

Swiss-port # Q9H1P3 Human Oxysterol-binding protein-related protein 2

Background This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. This encoded protein contains only the sterol-binding domain. In vitro studies have shown that the encoded protein can bind strongly to phosphatic acid and weakly to phosphatidylinositol 3-phosphate, but cannot bind to 25-hydroxycholesterol. The protein associates with the Golgi apparatus. Transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Research Area Cell Biology and Cellular Response antibody; Metabolism antibody; Signaling Transduction antibody
Calculated MW 55 kDa

Images (1) Click the Picture to Zoom In

  • ARG63387 anti-OSBPL2 / ORP2 antibody WB image

    Western blot: Human heart lysate (RIPA buffer, 30µg total protein per lane) stained with ARG63387 anti-OSBPL2 / ORP2 antibody at 1.5 µg/ml dilution.