ARG43297

anti-Neurotrophin 3 antibody

anti-Neurotrophin 3 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes Neurotrophin 3
Tested Reactivity Hu, Rat
Predict Reactivity Ms
Tested Application IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name Neurotrophin 3
Antigen Species Human
Immunogen Synthetic peptide corresponding to aa. 174-189 of Human Neurotrophin 3. (TVLGEIKTGNSPVKQY)
Conjugation Un-conjugated
Alternate Names Nerve growth factor 2; NT3; HDNF; Neurotrophic factor; Neurotrophin-3; NT-3; NGF2; NGF-2

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P1:200 - 1:1000
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Observed Size ~ 27 kDa

Properties

Form Liquid
Purification Affinity purification with immunogen.
Buffer 0.2% Na2HPO4, 0.9% NaCl, 0.05% Thimerosal, 0.05% Sodium azide and 5% BSA.
Preservative 0.05% Thimerosal and 0.05% Sodium azide
Stabilizer 5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 4908 Human NTF3

GeneID: 81737 Rat NTF3

Swiss-port # P18280 Rat Neurotrophin-3

Swiss-port # P20783 Human Neurotrophin-3

Gene Symbol NTF3
Gene Full Name neurotrophin 3
Background The protein encoded by this gene is a member of the neurotrophin family, that controls survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NTF3-deficient mice generated by gene targeting display severe movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse. [provided by RefSeq, Jul 2008]
Function Seems to promote the survival of visceral and proprioceptive sensory neurons. [UniProt]
Cellular Localization Secreted. [UniProt]
Calculated MW 29 kDa

Images (2) Click the Picture to Zoom In

  • ARG43297 anti-Neurotrophin 3 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Rat brain tissue stained with ARG43297 anti-Neurotrophin 3 antibody.

  • ARG43297 anti-Neurotrophin 3 antibody WB image

    Western blot: Rat brain, Rat brain, MCF7 and HeLa cell lysates stained with ARG43297 anti-Neurotrophin 3 antibody.