ARG45742
anti-NUP214 antibody
anti-NUP214 antibody for Flow cytometry,ICC/IF,Western blot and Human,Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes NUP214 |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | FACS, ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | NUP214 |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human NUP214. |
| Conjugation | Un-conjugated |
| Alternate Names | NUP214; Nucleoporin 214; CAIN; CAN; Nuclear Pore Complex Protein Nup214; CAN Protein, Putative Oncogene; Nucleoporin 214kDa; D9S46E; N214; Nucleoporin 214kD (CAIN); 214 KDa Nucleoporin; Nucleoporin Nup214; Protein CAN; KIAA0023; IIAE9 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Observed Size | 280 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
| Preservative | 0.05% Sodium azide |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P35658 Human Nuclear pore complex protein Nup214 Swiss-port # Q80U93 Mouse Nuclear pore complex protein Nup214 |
|---|---|
| Gene Symbol | NUP214 |
| Gene Full Name | Nucleoporin 214 |
| Background | The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. This gene is a member of the FG-repeat-containing nucleoporins. The protein encoded by this gene is localized to the cytoplasmic face of the nuclear pore complex where it is required for proper cell cycle progression and nucleocytoplasmic transport. The 3' portion of this gene forms a fusion gene with the DEK gene on chromosome 6 in a t(6,9) translocation associated with acute myeloid leukemia and myelodysplastic syndrome. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015] |
| Function | May serve as a docking site in the receptor-mediated import of substrates across the nuclear pore complex. [UniProt] |
| Cellular Localization | Nuclear pore complex; Nucleus. [UniProt] |
| Calculated MW | 214 kDa |
| PTM | Acetylation; Glycoprotein; Isopeptide bond; Phosphoprotein; Ubl conjugation. [UniProt] |
