ARG44117
anti-NUP133 antibody
anti-NUP133 antibody for Western blot and Human
Overview
Product Description | Rabbit Polyclonal recognizes NUP133 |
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Tested Reactivity | Hu |
Tested Application | WB |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Target Name | NUP133 |
Antigen Species | Human |
Immunogen | Human NUP133 recombinant protein (Position: Q228-I1156). |
Conjugation | Un-conjugated |
Alternate Names | NUP133; Nucleoporin 133; Nuclear Pore Complex Protein Nup133; 133 KDa Nucleoporin; Nucleoporin 133kDa; Nucleoporin Nup133; FLJ10814; Nucleoporin 133kD; HNUP133; GAMOS8; NPHS18 |
Application Instructions
Application Suggestion |
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Application Note | The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
Form | Liquid |
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Purification | Affinity purification with immunogen. |
Buffer | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
Preservative | 0.05% Sodium azide |
Stabilizer | 4% Trehalose |
Concentration | 0.5 mg/ml |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links |
Swiss-port # Q8WUM0 Human Nuclear pore complex protein Nup133 |
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Gene Symbol | NUP133 |
Gene Full Name | Nucleoporin 133 |
Background | The nuclear envelope creates distinct nuclear and cytoplasmic compartments in eukaryotic cells. It consists of two concentric membranes perforated by nuclear pores, large protein complexes that form aqueous channels to regulate the flow of macromolecules between the nucleus and the cytoplasm. These complexes are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. The nucleoporin protein encoded by this gene displays evolutionarily conserved interactions with other nucleoporins. This protein, which localizes to both sides of the nuclear pore complex at interphase, remains associated with the complex during mitosis and is targeted at early stages to the reforming nuclear envelope. This protein also localizes to kinetochores of mitotic cells. |
Function | Involved in poly(A)+ RNA transport. Involved in nephrogenesis. |
Cellular Localization | Centromere, Chromosome, Kinetochore, Nuclear pore complex, Nucleus |
Calculated MW | 129 kDa |
PTM | Acetylation, Methylation, Phosphoprotein |
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