ARG44111
anti-NUF2 antibody
anti-NUF2 antibody for Western blot and Human
Overview
| Product Description | Rabbit Polyclonal recognizes NUF2 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | NUF2 |
| Antigen Species | Human |
| Immunogen | Human NUF2 recombinant protein (Position: M1-Q297). |
| Conjugation | Un-conjugated |
| Alternate Names | NUF2; NUF2 Component Of NDC80 Kinetochore Complex; NUF2R; CT106; CDCA1; NDC80 Kinetochore Complex Component NUF2; Cell Division Cycle-Associated Protein 1; Cell Division Cycle Associated 1; Cancer/Testis Antigen 106; Kinetochore Protein Nuf2; HNuf2R; HsNuf2; HNuf2; NUF2, NDC80 Kinetochore Complex Component, Homolog (S. Cerevisiae); NUF2, NDC80 Kinetochore Complex Component, Homolog |
Application Instructions
| Application Suggestion |
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| Application Note | The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
| Preservative | 0.05% Sodium azide |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | NUF2 |
| Gene Full Name | NUF2 Component Of NDC80 Kinetochore Complex |
| Background | This gene encodes a protein that is highly similar to yeast Nuf2, a component of a conserved protein complex associated with the centromere. Yeast Nuf2 disappears from the centromere during meiotic prophase when centromeres lose their connection to the spindle pole body, and plays a regulatory role in chromosome segregation. The encoded protein is found to be associated with centromeres of mitotic HeLa cells, which suggests that this protein is a functional homolog of yeast Nuf2. Alternatively spliced transcript variants that encode the same protein have been described. |
| Function | Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. |
| Cellular Localization | Centromere, Chromosome, Kinetochore, Nucleus |
| Calculated MW | 54 kDa |
| PTM | Acetylation, Phosphoprotein |
Images (1) Click the Picture to Zoom In
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ARG44111 anti-NUF2 antibody WB image
Western blot: A431 and U251 stained with ARG44111 anti-NUF2 antibody at 0.5 μg/ml dilution.
