ARG41984

anti-NSD3 antibody

anti-NSD3 antibody for Flow cytometry,Western blot and Human,Mouse,Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes NSD3
Tested Reactivity Hu, Ms, Rat
Tested Application FACS, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name NSD3
Antigen Species Human
Immunogen Synthetic peptide of Human NSD3.
Conjugation Un-conjugated
Alternate Names Wolf-Hirschhorn syndrome candidate 1-like protein 1; WHSC1-like 1 isoform 9 with methyltransferase activity to lysine; EC 2.1.1.43; WHSC1-like protein 1; Histone-lysine N-methyltransferase NSD3; NSD3; Protein whistle; Nuclear SET domain-containing protein 3; pp14328

Application Instructions

Application Suggestion
Tested Application Dilution
FACS1:30
WB1:1000 - 1:5000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control MCF7

Properties

Form Liquid
Purification Affinity purified.
Buffer PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 234135 Mouse WHSC1L1

GeneID: 54904 Human WHSC1L1

Swiss-port # Q6P2L6 Mouse Histone-lysine N-methyltransferase NSD3

Swiss-port # Q9BZ95 Human Histone-lysine N-methyltransferase NSD3

Gene Symbol WHSC1L1
Gene Full Name Wolf-Hirschhorn syndrome candidate 1-like 1
Background This gene is related to the Wolf-Hirschhorn syndrome candidate-1 gene and encodes a protein with PWWP (proline-tryptophan-tryptophan-proline) domains. This protein methylates histone H3 at lysine residues 4 and 27, which represses gene transcription. Two alternatively spliced variants have been described. [provided by RefSeq, May 2015]
Function Histone methyltransferase. Preferentially methylates 'Lys-4' and 'Lys-27' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation, while 'Lys-27' is a mark for transcriptional repression. [UniProt]
Cellular Localization Nucleus. Chromosome. [UniProt]
Calculated MW 162 kDa

Images (1) Click the Picture to Zoom In

  • ARG41984 anti-NSD3 antibody WB image

    Western blot: MCF7 cell lysate stained with ARG41984 anti-NSD3 antibody.