ARG57969
anti-NRP2 antibody
anti-NRP2 antibody for Western blot and Mouse,Rat
Overview
Product Description | Rabbit Polyclonal antibody recognizes NRP2 |
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Tested Reactivity | Ms, Rat |
Tested Application | WB |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Target Name | NRP2 |
Antigen Species | Human |
Immunogen | Recombinant fusion protein corresponding to aa. 443-740 of Human NRP2 (NP_003863.2). |
Conjugation | Un-conjugated |
Alternate Names | PRO2714; Neuropilin-2; Vascular endothelial cell growth factor 165 receptor 2; NPN2; NP2; VEGF165R2 |
Application Instructions
Application Suggestion |
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Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
Positive Control | Rat kidney | ||||
Observed Size | ~ 95 kDa |
Properties
Form | Liquid |
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Purification | Affinity purified. |
Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
Preservative | 0.02% Sodium azide |
Stabilizer | 50% Glycerol |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links | |
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Gene Symbol | NRP2 |
Gene Full Name | neuropilin 2 |
Background | This gene encodes a member of the neuropilin family of receptor proteins. The encoded transmembrane protein binds to SEMA3C protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C} and SEMA3F protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F}, and interacts with vascular endothelial growth factor (VEGF). This protein may play a role in cardiovascular development, axon guidance, and tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] |
Function | High affinity receptor for semaphorins 3C, 3F, VEGF-165 and VEGF-145 isoforms of VEGF, and the PLGF-2 isoform of PGF. [UniProt] |
Cellular Localization | Membrane, Secreted, Single-pass type I membrane protein. [UniProt] |
Calculated MW | 105 kDa |
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