ARG42219

anti-NPY1R antibody

anti-NPY1R antibody for Western blot and Human,Mouse

Overview

Product Description Rabbit Polyclonal antibody recognizes NPY1R
Tested Reactivity Hu, Ms
Tested Application WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name NPY1R
Antigen Species Human
Immunogen Synthetic peptide of Human NPY1R.
Conjugation Un-conjugated
Alternate Names NPYR; Neuropeptide Y receptor type 1; NPY1-R

Application Instructions

Application Suggestion
Tested Application Dilution
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control Mouse fetal brain
Observed Size ~ 43 kDa

Properties

Form Liquid
Purification Affinity purified.
Buffer PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 18166 Mouse NPY1R

GeneID: 4886 Human NPY1R

Swiss-port # P25929 Human Neuropeptide Y receptor type 1

Swiss-port # Q04573 Mouse Neuropeptide Y receptor type 1

Gene Symbol NPY1R
Gene Full Name neuropeptide Y receptor Y1
Background This gene belongs to the G-protein-coupled receptor superfamily. The encoded transmembrane protein mediates the function of neuropeptide Y (NPY), a neurotransmitter, and peptide YY (PYY), a gastrointestinal hormone. The encoded receptor undergoes fast agonist-induced internalization through clathrin-coated pits and is subsequently recycled back to the cell membrane. Activation of Y1 receptors may result in mobilization of intracellular calcium and inhibition of adenylate cyclase activity. [provided by RefSeq, Aug 2013]
Function Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is NPY > [Pro-34] PYY, PYY and [Leu-31, Pro-34] NPY > NPY (2-36) > [Ile-31, Gln-34] PP and PYY (3-36) > PP > NPY free acid. [UniProt]
Cellular Localization Cell membrane; Multi-pass membrane protein. [UniProt]
Calculated MW 44 kDa

Images (1) Click the Picture to Zoom In

  • ARG42219 anti-NPY1R antibody WB image

    Western blot: 25 µg of Mouse fetal brain lysate stained with ARG42219 anti-NPY1R antibody.