ARG44568
anti-NETO2 antibody
anti-NETO2 antibody for Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes NETO2 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | NETO2 |
| Antigen Species | Human |
| Immunogen | Human NETO2 recombinant protein (aa. sequence: I23-F525). |
| Conjugation | Un-conjugated |
| Alternate Names | NETO2; Neuropilin And Tolloid Like 2; NEOT2; Brain-Specific Transmembrane Protein Containing 2 CUB And 1 LDL-Receptor Class A Domains Protein 2; Neuropilin (NRP) And Tolloid (TLL)-Like 2; Neuropilin And Tolloid-Like Protein 2; FLJ10430; BTCL2 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Preservative | 4% Trehalose |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | NETO2 |
| Gene Full Name | Neuropilin And Tolloid Like 2 |
| Background | This gene encodes a predicted transmembrane protein containing two extracellular CUB domains followed by a low-density lipoprotein class A (LDLa) domain. A similar gene in rats encodes a protein that modulates glutamate signaling in the brain by regulating kainate receptor function. Expression of this gene may be a biomarker for proliferating infantile hemangiomas. A pseudogene of this gene is located on the long arm of chromosome 8. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011] |
| Function | Accessory subunit of neuronal kainate-sensitive glutamate receptors, GRIK2 and GRIK3. Increases kainate-receptor channel activity, slowing the decay kinetics of the receptors, without affecting their expression at the cell surface, and increasing the open probability of the receptor channels. Modulates the agonist sensitivity of kainate receptors. Slows the decay of kainate receptor-mediated excitatory postsynaptic currents (EPSCs), thus directly influencing synaptic transmission. [Uniprot] |
| Cellular Localization | Membrane. [Uniprot] |
| Calculated MW | 59 kDa |
| PTM | Disulfide bond, Glycoprotein, Phosphoprotein. [Uniprot] |
Images (3) Click the Picture to Zoom In
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ARG44568 anti-NETO2 antibody WB image
Western blot: SIHA and SH-SY5Y stained with ARG44568 anti-NETO2 antibody at 0.5 μg/mL dilution.
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ARG44568 anti-NETO2 antibody WB image
Western blot: Rat brain and C6 stained with ARG44568 anti-NETO2 antibody at 0.5 μg/mL dilution.
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ARG44568 anti-NETO2 antibody WB image
Western blot: Mouse brain and Neuro-2a stained with ARG44568 anti-NETO2 antibody at 0.5 μg/mL dilution.
