ARG44567

anti-NETO1 antibody

anti-NETO1 antibody for Western blot and Human,Mouse,Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes NETO1
Tested Reactivity Hu, Ms, Rat
Tested Application WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name NETO1
Antigen Species Human
Immunogen Human NETO1 recombinant protein (aa. sequence: R5-R514).
Conjugation Un-conjugated
Alternate Names NETO1; Neuropilin And Tolloid Like 1; BTCL1; BCTL1; Brain-Specific Transmembrane Protein Containing 2 CUB And 1 LDL-Receptor Class A Domains Protein 1; Neuropilin (NRP) And Tolloid (TLL)-Like 1; Neuropilin And Tolloid-Like Protein 1

Application Instructions

Application Suggestion
Tested Application Dilution
WB0.25-0.5 µg/ml
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Affinity purified.
Buffer 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose.
Preservative 4% Trehalose
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 246317 Mouse NETO1

GeneID: 81832 Human NETO1

Swiss-port # Q8R4I7 Mouse Neuropilin and tolloid-like protein 1

Swiss-port # Q8TDF5 Human Neuropilin and tolloid-like protein 1

Gene Symbol NETO1
Gene Full Name Neuropilin And Tolloid Like 1
Background This gene encodes a transmembrane protein containing two extracellular CUB domains followed by a low-density lipoprotein class A (LDLa) domain. This protein is thought to play a critical role in spatial learning and memory by regulating the function of synaptic N-methyl-D-aspartic acid receptor complexes in the hippocampus. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2017]
Function Involved in the development and/or maintenance of neuronal circuitry. Accessory subunit of the neuronal N-methyl-D-aspartate receptor (NMDAR) critical for maintaining the abundance of GRIN2A-containing NMDARs in the postsynaptic density. Regulates long-term NMDA receptor-dependent synaptic plasticity and cognition, at least in the context of spatial learning and memory. [Uniprot]
Cellular Localization Cell membrane, Membrane, Postsynaptic cell membrane, Secreted, Synapse. [Uniprot]
Calculated MW 60 kDa
PTM Disulfide bond, Glycoprotein, Phosphoprotein. [Uniprot]

Images (1) Click the Picture to Zoom In

  • ARG44567 anti-NETO1 antibody WB image

    Western blot: U20S, PC-3 and SIHA stained with ARG44567 anti-NETO1 antibody at 0.5 μg/mL dilution.