ARG65564
anti-NDUFA2 antibody
anti-NDUFA2 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse
Cancer antibody; Controls and Markers antibody; Metabolism antibody; Signaling Transduction antibody
Overview
| Product Description | Rabbit Polyclonal antibody recognizes NDUFA2 |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | NDUFA2 |
| Antigen Species | Human |
| Immunogen | Fusion protein of human NDUFA2 |
| Conjugation | Un-conjugated |
| Alternate Names | CI-B8; Complex I-B8; CD14; NADH-ubiquinone oxidoreductase B8 subunit; CIB8; B8; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Positive Control | Raw264.7 cell |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified by antigen-affinity chromatography. |
| Buffer | 1XPBS (pH 7.4), 0.05% Sodium azide and 40% Glycerol |
| Preservative | 0.05% Sodium azide |
| Stabilizer | 40% Glycerol |
| Concentration | 1.9 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # O43678 Human NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 Swiss-port # Q9CQ75 Mouse NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 |
|---|---|
| Gene Symbol | NDUFA2 |
| Gene Full Name | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa |
| Background | The encoded protein is a subunit of the hydrophobic protein fraction of the NADH:ubiquinone oxidoreductase (complex 1), the first enzyme complex in the electron transport chain located in the inner mitochondrial membrane, and may be involved in regulating complex I activity or its assembly via assistance in redox processes. Mutations in this gene are associated with Leigh syndrome, an early-onset progressive neurodegenerative disorder. |
| Function | Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. [UniProt] |
| Highlight | Related products: NDUFA2 antibodies; Anti-Rabbit IgG secondary antibodies; Related poster download: The Structure & Functions of Mitochondria.pdf |
| Research Area | Cancer antibody; Controls and Markers antibody; Metabolism antibody; Signaling Transduction antibody |
| Calculated MW | 11 kDa |
Images (2) Click the Picture to Zoom In
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ARG65564 anti-NDUFA2 antibody WB image
Western blot: ARG65564 anti-NDUFA2 antibody at 1/300 dilution with 40 μg of Raw264.7 cell lysate.
Exporsure time: 5 seconds. -
ARG65564 anti-NDUFA2 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human thyroid cancer tissue stained with ARG65564 anti-NDUFA2 antibody (left) at 1/30 dilution, or the same antibody preincubated with fusion protein (right). (Original magnification: ×200).
